Suppr超能文献

A comparative study of biochemical changes induced by inhalation of aerosols of o-Chloroacetophenone & Dibenz (b,f)-1,4-oxazepine in rats.

作者信息

Husain K, Kumar P, Malhotra R C

机构信息

Division of Toxicology & Pharmacology, Defence Research & Development Establishment, Gwalior.

出版信息

Indian J Med Res. 1991 Feb;94:76-9.

PMID:2071189
Abstract

The biochemical changes in blood samples of rats at different intervals after O-Chloroacetophenone (CN) and Dibenz (b,f)-1,4 oxazepine (CR) were studied. After a single subacute (1/10 LC50) exposure, both the compounds induced hyperglycaemia which was abolished within 24 h. The level of plasma urea was unaltered. CR exposed animals did not show any significant changes in plasma GOT, acid and alkaline phosphatase activities at different intervals. However, in CN exposed animals, a significant elevation of the activities of GOT, GPT, acid and alkaline phosphatase was observed at different intervals. All the parameters became normal within seven days after the exposure. Inhalation of CN aerosols can thus lead to tissue damaging effects in rats.

摘要

相似文献

1
A comparative study of biochemical changes induced by inhalation of aerosols of o-Chloroacetophenone & Dibenz (b,f)-1,4-oxazepine in rats.
Indian J Med Res. 1991 Feb;94:76-9.
2
Time dependent histomorphological assessment of lung damage induced by inhaled dibenz(b,f)-1-4-oxazepine (CR) and 1-chloroacetophenone (CN) in rats.大鼠吸入二苯并(b,f)-1,4-恶唑嗪(CR)和氯苯乙酮(CN)所致肺损伤的时间依赖性组织形态学评估
Funct Dev Morphol. 1993;3(3):181-4.
3
Effect of inhaled aerosol of 1-chloroacetophenone (CN) and Dibenz (b,f)-1,4 oxazepine (CR) on lung mechanics and pulmonary surfactants in rats.吸入1-氯苯乙酮（CN）和二苯并（b，f）-1,4-恶唑嗪（CR）气雾剂对大鼠肺力学和肺表面活性剂的影响。
Hum Exp Toxicol. 1995 May;14(5):404-9. doi: 10.1177/096032719501400503.
4
Toxicological evaluation of 1-chloroacetophenone and dibenz[b,f]-1,4-oxazepine after repeated inhalation exposure in mice.小鼠反复吸入暴露后对1-氯苯乙酮和二苯并[b,f]-1,4-恶唑嗪的毒理学评价。
J Appl Toxicol. 1994 Nov-Dec;14(6):411-6. doi: 10.1002/jat.2550140605.
5
The acute mammalian toxicology of dibenz(b,f)-1,4-oxazepine.二苯并(b,f)-1,4-恶唑嗪的急性哺乳动物毒理学
Toxicology. 1977 Dec;8(3):347-79. doi: 10.1016/0300-483x(77)90082-8.
6
The comparative ophthalmic toxicology of 1-chloroacetophenone (CN) and dibenz(b.f)-1:4-oxazepine(CR).
Arch Toxicol. 1975 Nov 20;34(3):183-201. doi: 10.1007/BF00353282.
7
Tear gases and irritant incapacitants. 1-chloroacetophenone, 2-chlorobenzylidene malononitrile and dibenz[b,f]-1,4-oxazepine.催泪瓦斯和刺激性失能剂。1-氯苯乙酮、2-氯亚苄基丙二腈和二苯并[b,f]-1,4-恶唑并[4,5-b]氮杂卓
Toxicol Rev. 2003;22(2):103-10. doi: 10.2165/00139709-200322020-00005.
8
Effect of methyl substitution on the irritancy of dibenz[b,f]1,4-oxazepine(CR).甲基取代对二苯并[b,f][1,4]恶唑磷（CR）刺激性的影响。
Toxicology. 1979 Feb;12(2):151-3. doi: 10.1016/0300-483x(79)90041-6.
9
The cutaneous reactions produced by dibenzoxazepine (CR).二苯并恶唑嗪产生的皮肤反应（CR）。
Br J Dermatol. 1974 Jun;90(6):657-9. doi: 10.1111/j.1365-2133.1974.tb06694.x.
10
The comparative acute mammalian toxicity of 1-chloroacetophenone (CN) and 2-chlorobenzylidene malononitrile (CS).1-氯苯乙酮（CN）和2-氯苄叉丙二腈（CS）的急性哺乳动物毒性比较
Arch Toxicol. 1978 Apr 27;40(2):75-95. doi: 10.1007/BF01891962.

引用本文的文献

1
Effects of omega-chloroacetophenone (CN) vapor inhalation on pulmonary immune system of mice.
Bull Environ Contam Toxicol. 1993 Jan;50(1):69-76. doi: 10.1007/BF00196543.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验