Lasker Judith N, Sogolow Ellen D, Olenik Jennifer M, Sass David A, Weinrieb Robert M
Department of Sociology & Anthropology, Lehigh University, Bethlehem, Pennsylvania 18015, USA.
Women Health. 2010 Jun;50(4):359-75. doi: 10.1080/03630242.2010.498750.
Uncertainty is a frequent feature of chronic illness and can have a particularly important impact in the case of organ transplantation. This study of 100 women with primary biliary cirrhosis who were either waiting for or had already had a liver transplant focused on both changes in uncertainty with transplant and the correlates of uncertainty both pre- and post-transplant. While those who were post-transplant had significantly lower uncertainty scores (measured by the Mishel Uncertainty in Illness Scale-Adult Version-MUIS-A) than those on the waiting list, uncertainty was still persistent and associated with a reduced quality of life. The most significant factors in relation to uncertainty were fatigue, depression, anxiety, and dissatisfaction with medical information received. It is important for both patients and transplant team members to recognize the impact of uncertainty on a patient's well-being, both before and after a transplant, and to address the underlying factors that continue to compromise quality of life even after a life-saving procedure.
不确定性是慢性病的常见特征，在器官移植的情况下可能会产生特别重要的影响。这项针对100名原发性胆汁性肝硬化女性的研究，她们要么正在等待肝移植，要么已经接受了肝移植，研究重点是移植前后不确定性的变化以及不确定性的相关因素。虽然移植后的患者不确定性得分（通过成人疾病不确定性量表 - 米歇尔量表 - MUIS - A测量）明显低于等待名单上的患者，但不确定性仍然存在，并与生活质量下降相关。与不确定性最相关的因素是疲劳、抑郁、焦虑以及对所获得医疗信息的不满。对于患者和移植团队成员来说，认识到不确定性在移植前后对患者幸福感的影响，并解决即使在进行了挽救生命的手术后仍继续影响生活质量的潜在因素非常重要。
