Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
BMC Musculoskelet Disord. 2010 Aug 16;11:183. doi: 10.1186/1471-2474-11-183.
By analyzing the clinical features and risk factors in female patients with musculoskeletal symptoms of Southwest China, this report presents the initial analysis of characteristics in this region and compared with international evaluative criteria.
Diagnosis of osteoporosis (OP) was made in female hospital patients age > or = 18 years admitted from January 1998 to December 2008 according to WHO definition. Case data were analyzed by symptoms, age, disease course and risk factors to reveal correlation with diagnosis of OP. Logistic regression was used to identify the risks of osteoporosis.
A total of 4382 patients were included in the analysis of the baseline characteristics, among which 1455 in the OP group and 2927 in the non-OP group. The morbidity of OP is significantly increased in females' > or = 50 years. Both groups had symptoms related to pain and numbness; no significant difference was found in reported upper and lower back pain, or leg pain between two groups (p > 0.05). Neck, shoulder and arm pain, leg and arm numbness were more common in the non-osteoporosis group (p < 0.05, OR < 1, and upper limit of 95% CI of OR < 1). Hypertension, diabetes, hyperostosis were major risk factors for the patients with OP. The most common lifestyle-related risk factors for osteoporosis were smoking, body mass index, lack of physical activity and menopause.
The present study offers the first reference data of the relationship between epidemiologic distribution of osteoporosis and associated factors in adults Chinese women. These findings provide a theoretical basis for its prevention and treatment in developing country.
通过分析中国西南地区女性肌肉骨骼症状患者的临床特征和危险因素，本报告首次分析了该地区的特点，并与国际评估标准进行了比较。
根据世界卫生组织的定义，对 1998 年 1 月至 2008 年 12 月期间年龄≥18 岁的住院女性骨质疏松症（OP）患者进行诊断。通过症状、年龄、病程和危险因素分析来揭示与 OP 诊断的相关性。采用 Logistic 回归识别骨质疏松症的风险因素。
共纳入 4382 例患者进行基线特征分析，其中 OP 组 1455 例，非 OP 组 2927 例。女性≥50 岁的骨质疏松症发病率显著增加。两组均有与疼痛和麻木相关的症状；两组报告的腰背疼痛或腿痛无显著差异（p＞0.05）。非骨质疏松组更常见颈、肩、臂疼痛和腿、臂麻木（p＜0.05，OR＜1，OR 的 95%CI 上限＜1）。高血压、糖尿病、骨质增生是 OP 患者的主要危险因素。与骨质疏松症相关的最常见生活方式危险因素是吸烟、体重指数、缺乏体育活动和绝经。
本研究提供了中国成年女性骨质疏松症流行病学分布与相关因素关系的首批参考数据。这些发现为发展中国家的预防和治疗提供了理论依据。
