Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, Academia, 20 College Road, Singapore, 169856, Singapore.
HealthWords Ltd, Augusta, GA, USA.
Osteoporos Int. 2023 Jun;34(6):1037-1053. doi: 10.1007/s00198-022-06657-8. Epub 2023 Feb 3.
Robust data on osteoporosis in the Asia Pacific region could improve healthcare decision-making. Osteoporosis affects 10-30% of women aged 40 + , and up to 10% of men in 7 developed economies in Asia Pacific. Fractures affect 500-1000 adults aged 50 + per 100,000 person-years. Policymakers and clinicians must address this problem.
Osteoporosis and associated fractures result in considerable morbidity, loss of productivity, early mortality, and increased healthcare expenses. Many countries in the Asia Pacific (AP) region, especially middle- and higher-income economies, are faced with aging and increasingly sedentary populations. It is critical to consolidate and analyze the available information on the prevalence and incidence of the disease in these countries.
We systematically reviewed articles and gray literature for Australia, China, Hong Kong, Japan, Singapore, South Korea, and Taiwan. We searched PubMed, ScienceDirect, JSTOR, Cochrane, Google Scholar, and other databases for data published 2009-2018. We included articles with prevalence or incidence estimates for adults with osteoporosis or related fractures.
All locations had data available, but of widely varying quantity and quality. Most estimates for osteoporosis prevalence ranged from 10 to 30% for women ages 40 and older, and up to 10% for men. Osteoporotic fracture incidence typically ranged between 500 and 1000 per 100,000 person-years among adults aged 50 and older. Both outcomes typically increased with age and were more common among women.
Osteoporosis and associated fractures affect significant portions of the adult population in developed economies in the AP region. Governments and healthcare systems must consider how best to prevent and diagnose osteoporosis, and manage affected individuals, to reduce healthcare costs and mortality associated with fractures.
在亚太地区，关于骨质疏松症的可靠数据可以改善医疗保健决策。骨质疏松症影响了 10-30%的 40 岁以上女性，以及 7 个发达亚洲太平洋经济体中 10%的男性。骨折影响了 500-1000 名 50 岁以上成年人，每 10 万人中有 0.5-1 人骨折。政策制定者和临床医生必须解决这个问题。
骨质疏松症和相关骨折会导致相当大的发病率、生产力丧失、早逝和增加医疗保健费用。亚太地区（AP）的许多国家，特别是中等和高收入经济体，都面临着人口老龄化和日益久坐不动的问题。关键是要整合和分析这些国家有关疾病患病率和发病率的现有信息。
我们系统地回顾了澳大利亚、中国、中国香港、日本、新加坡、韩国和中国台湾的文章和灰色文献。我们在 PubMed、ScienceDirect、JSTOR、Cochrane、Google Scholar 和其他数据库中搜索了 2009 年至 2018 年期间发表的数据。我们纳入了关于骨质疏松症或相关骨折的成年人患病率或发病率估计的文章。
所有地点都有数据，但数量和质量差异很大。大多数骨质疏松症患病率的估计值为 40 岁及以上女性的 10-30%，男性的 10%。50 岁及以上成年人的骨质疏松性骨折发生率通常在每 10 万人中有 500-1000 人之间。这两种结果通常随着年龄的增长而增加，并且在女性中更为常见。
在亚太地区发达经济体中，骨质疏松症和相关骨折影响了相当大一部分成年人口。政府和医疗保健系统必须考虑如何最好地预防和诊断骨质疏松症，并管理受影响的个体，以降低与骨折相关的医疗保健成本和死亡率。
