Virginia Polytechnic Institute and State University, Human Nutrition, Foods, and Exercise, VT Riverside, Roanoke, VA 24016, USA.
Prev Chronic Dis. 2010 Sep;7(5):A103. Epub 2010 Aug 15.
Although lifestyle interventions are effective in delaying the onset of diabetes, translating these lessons to routine health care settings remains a challenge. We investigated the effectiveness of a theory-based, brief, small-group weight loss intervention for diabetes prevention. A secondary purpose was to determine the potential reach of the intervention.
A total of 14,379 members of an integrated health care organization newly diagnosed with prediabetes were potentially eligible to participate in this matched cohort longitudinal study. Of this group, 1,030 attended a 90-minute, small-group session that targeted personal action planning for healthful eating, physical activity, and weight management. We accessed electronic medical records to select 1 to 2 controls (matched on impaired fasting glucose measurement, sex, age, and body mass index) for each member who attended the small-group session (n = 760). Weight change, as recorded in the medical record, was the primary outcome. Mixed models analyses were used to adjust for matching variables and covariates and to account for individual random effects over time.
Small-group participants lost significantly more weight than did their matched controls. A significantly higher proportion of small-group participants lost at least 5% of their body weight compared with controls.
A brief, small-group weight loss intervention was effective. However, it did not reach broadly into the population that was at risk for diabetes.
尽管生活方式干预可有效延缓糖尿病的发病，但将这些经验转化为常规医疗保健环境仍然具有挑战性。我们研究了一种基于理论、简短、小组形式的减肥干预措施在预防糖尿病方面的有效性。次要目的是确定干预措施的潜在覆盖范围。
共有 14379 名被诊断患有前期糖尿病的综合性医疗保健组织成员有资格参加这项匹配队列纵向研究。在这一组中，有 1030 人参加了一个 90 分钟的小组会议，该会议针对健康饮食、身体活动和体重管理方面的个人行动计划。我们查阅电子病历，为参加小组会议的每位成员（n=760）选择 1 到 2 名对照者（匹配空腹血糖测量、性别、年龄和体重指数受损）。体重变化（记录在医疗记录中）是主要结果。混合模型分析用于调整匹配变量和协变量，并考虑个体随时间的随机效应。
小组参与者的体重减轻明显多于对照组。与对照组相比，小组参与者中体重减轻至少 5%的比例显著更高。
简短的小组减肥干预措施是有效的。然而，它并没有广泛覆盖到有患糖尿病风险的人群。
