Department of Human Biology, Maastricht University, Maastricht, The Netherlands.
Int J Obes (Lond). 2010 Oct;34(10):1508-14. doi: 10.1038/ijo.2010.161. Epub 2010 Aug 17.
Short sleep duration is associated with obesity during childhood and adulthood.
The objective of our study was to investigate the relationship between sleep duration and body mass index (BMI) from Tanner stages 1 to 5 in a Dutch children cohort.
In 98 children, anthropometric measurements and leptin concentrations were measured from age 7 to 16 years; body composition, physical activity (Baecke questionnaire), hours television viewing and self-reported sleep duration were measured yearly from age 12 to 16 years. Moreover, the polymorphisms of the FTO gene (rs9939609) and parental BMI's were determined.
At Tanner stages 1-5 sex differences were observed in height, body weight, waist circumference, fat mass per squared meter height and leptin concentrations per kg fat mass. Inverse relationships were observed between the change in BMI (kg m(-2)) and the change in hours of sleep per night (h) from Tanner stages 1 to 4 (r=-0.68, P<0.001), from Tanner stages 2 to 5 (r=-0.35, P<0.05) and from Tanner stages 1 to 5 (r=-0.33, P<0.05). Univariate analysis of variance showed that with progressive Tanner stages, BMI increases and sleep duration decreases in an interrelated way independent of possible confounders (R(2)=0.38, P<0.02).
Changes in BMI during puberty were inversely related to changes in sleep duration, independent of possible confounders.
睡眠时间短与儿童期和成年期肥胖有关。
我们的研究目的是在荷兰儿童队列中，从 Tanner 分期 1 期到 5 期调查睡眠时间与体重指数（BMI）之间的关系。
在 98 名儿童中，从 7 岁到 16 岁测量了人体测量学测量值和瘦素浓度；从 12 岁到 16 岁，每年测量身体成分、体力活动（Baecke 问卷）、看电视时间和自我报告的睡眠时间。此外，还确定了 FTO 基因（rs9939609）的多态性和父母的 BMI。
在 Tanner 分期 1-5 期，身高、体重、腰围、每平方米身高的脂肪量和每公斤脂肪量的瘦素浓度存在性别差异。从 Tanner 分期 1 到 4 期（r=-0.68，P<0.001）、从 Tanner 分期 2 到 5 期（r=-0.35，P<0.05）和从 Tanner 分期 1 到 5 期（r=-0.33，P<0.05），观察到 BMI（kg/m2）的变化与每晚睡眠时间（h）的变化之间存在负相关。单变量方差分析显示，随着 Tanner 分期的进展，BMI 增加，睡眠时间减少，这种相互关系独立于可能的混杂因素（R2=0.38，P<0.02）。
青春期 BMI 的变化与睡眠时间的变化呈负相关，与可能的混杂因素无关。
