Collings Paul J, Wijndaele Katrien, Corder Kirsten, Westgate Kate, Ridgway Charlotte L, Sharp Stephen J, Atkin Andrew J, Bamber Diane, Goodyer Ian, Brage Soren, Ekelund Ulf
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Sleep Med. 2015 Jun;16(6):717-22. doi: 10.1016/j.sleep.2015.02.532. Epub 2015 Mar 24.
The objective of this study was to investigate whether objectively measured sedentary time and sleep duration are associated with changes in adiposity from mid- to late adolescence.
Students (n = 504, 42% boys) were recruited from schools in Cambridgeshire, UK. At baseline (mean age 15.0 ± 0.3 years), sedentary time was objectively measured by ≥3 days of combined heart rate and movement sensing. Concurrently, sleep duration was measured by combined sensing in conjunction with self-reported bed times. Fat mass index (FMI; kg/m(2)) was estimated at baseline and follow-up (17.5 ± 0.3 years) by anthropometry and bioelectrical impedance. FMI change (ΔFMI) was calculated by subtracting the baseline from follow-up values. Linear regression models adjusted for basic demographics, moderate-to-vigorous physical activity (MVPA), and depressive symptoms were used to investigate associations of sedentary time and sleep duration (mutually adjusted for one another) with ΔFMI.
FMI increased by 0.5 and 0.6 kg/m(2) in boys and girls, respectively, but there was no association between sedentary time and ΔFMI in either gender (p ≥ 0.087), and no association between sleep duration and ΔFMI in girls (p ≥ 0.61). In boys, each additional hour of baseline sleep significantly reduced the ΔFMI by 0.13 kg/m(2) (p = 0.049), but there was little evidence for this association after adjusting for MVPA and depressive symptoms (p = 0.15).
Sedentary time may not determine changes in adiposity from mid- to late adolescence, nor may sleep duration in girls. However, sleep length may be inversely associated with adiposity gain in boys, depending on whether the relationship is confounded or mediated by MVPA and depression.
本研究旨在调查客观测量的久坐时间和睡眠时间是否与青少年中期到晚期的肥胖变化有关。
从英国剑桥郡的学校招募学生（n = 504，42%为男孩）。在基线时（平均年龄15.0±0.3岁），通过≥3天的心率和运动传感组合客观测量久坐时间。同时，通过传感组合结合自我报告的就寝时间测量睡眠时间。在基线和随访时（17.5±0.3岁）通过人体测量和生物电阻抗估计脂肪量指数（FMI；kg/m²）。FMI变化（ΔFMI）通过随访值减去基线值计算得出。使用针对基本人口统计学、中度至剧烈身体活动（MVPA）和抑郁症状进行调整的线性回归模型来研究久坐时间和睡眠时间（相互调整）与ΔFMI的关联。
男孩和女孩的FMI分别增加了0.5和0.6 kg/m²，但久坐时间与任何性别的ΔFMI均无关联（p≥0.087），女孩的睡眠时间与ΔFMI也无关联（p≥0.61）。在男孩中，基线睡眠每增加一小时，ΔFMI显著降低0.13 kg/m²（p = 0.049），但在调整MVPA和抑郁症状后，这种关联的证据不足（p = 0.15）。
久坐时间可能无法决定青少年中期到晚期的肥胖变化，女孩的睡眠时间也可能如此。然而，睡眠时长可能与男孩的肥胖增加呈负相关，这取决于这种关系是否被MVPA和抑郁所混淆或介导。
