School of Chemistry and Chemical Engineering; State of Key Laboratory of Coordination, Nanjing University, Nanjing, 210093, China.
Org Biomol Chem. 2010 Oct 7;8(19):4236-9. doi: 10.1039/c0ob00283f. Epub 2010 Aug 13.
A novel copper-catalyzed aminobromination-elimination process has been developed, which provides an easy access to alpha,beta-unsaturated vicinal haloamindes derivatives from readily available alpha,beta-unsaturated ketones and esters in good to excellent yields. The isolated intermediate discloses that the current system proceeds through the aminobromination process.
一种新型的铜催化氨基溴化-消除反应已经被开发出来，该方法为从易得的α,β-不饱和酮和酯中以良好至优秀的收率得到α,β-不饱和邻卤代氨基化合物衍生物提供了一条便捷途径。分离得到的中间体表明该反应是通过氨基溴化过程进行的。
