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1
Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin.
Angew Chem Int Ed Engl. 2010 Sep 17;49(39):7030-4. doi: 10.1002/anie.201002906.
3
Cyclotides, a versatile ultrastable micro-protein scaffold for biotechnological applications.
Bioorg Med Chem Lett. 2017 Dec 1;27(23):5089-5099. doi: 10.1016/j.bmcl.2017.10.051. Epub 2017 Oct 21.
4
Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor.
J Biol Chem. 2013 Dec 13;288(50):36141-8. doi: 10.1074/jbc.M113.528240. Epub 2013 Oct 29.
7
Oxidative folding of the cystine knot motif in cyclotide proteins.
Protein Pept Lett. 2005 Feb;12(2):147-52. doi: 10.2174/0929866053005863.
8
Circular proteins in plants: solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis.
J Biol Chem. 2001 Jun 22;276(25):22875-82. doi: 10.1074/jbc.M101666200. Epub 2001 Apr 5.
9
Cyclotides, a promising molecular scaffold for peptide-based therapeutics.
Biopolymers. 2010;94(5):611-6. doi: 10.1002/bip.21433.
10
Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways.
J Control Release. 2011 Oct 30;155(2):134-43. doi: 10.1016/j.jconrel.2011.08.030. Epub 2011 Aug 30.

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1
Using the Cyclotide Scaffold for Targeting Biomolecular Interactions in Drug Development.
Molecules. 2022 Sep 29;27(19):6430. doi: 10.3390/molecules27196430.
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Engineered Cyclotides with Potent Broad in Vitro and in Vivo Antimicrobial Activity.
Chemistry. 2021 Sep 1;27(49):12702-12708. doi: 10.1002/chem.202101438. Epub 2021 Aug 6.
3
Recombinant Expression of Cyclotides Using Expressed Protein Ligation.
Methods Mol Biol. 2020;2133:327-341. doi: 10.1007/978-1-0716-0434-2_16.
4
The Potential of the Cyclotide Scaffold for Drug Development.
Biomedicines. 2019 Apr 19;7(2):31. doi: 10.3390/biomedicines7020031.
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Cyclotides, a versatile ultrastable micro-protein scaffold for biotechnological applications.
Bioorg Med Chem Lett. 2017 Dec 1;27(23):5089-5099. doi: 10.1016/j.bmcl.2017.10.051. Epub 2017 Oct 21.
6
In vivo Evaluation of an Engineered Cyclotide as Specific CXCR4 Imaging Reagent.
Chemistry. 2017 Oct 17;23(58):14469-14475. doi: 10.1002/chem.201702540. Epub 2017 Aug 3.
7
Cyclotides: Overview and Biotechnological Applications.
Chembiochem. 2017 Jul 18;18(14):1350-1363. doi: 10.1002/cbic.201700153. Epub 2017 May 24.
8
Full Sequence Amino Acid Scanning of θ-Defensin RTD-1 Yields a Potent Anthrax Lethal Factor Protease Inhibitor.
J Med Chem. 2017 Mar 9;60(5):1916-1927. doi: 10.1021/acs.jmedchem.6b01689. Epub 2017 Feb 14.
9
Recombinant Expression of Cyclotides Using Split Inteins.
Methods Mol Biol. 2017;1495:41-55. doi: 10.1007/978-1-4939-6451-2_4.
10
Chemical and biological production of cyclotides.
Adv Bot Res. 2015;76:271-303. doi: 10.1016/bs.abr.2015.08.006.

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Chemical Synthesis of a Circular Protein Domain: Evidence for Folding-Assisted Cyclization.
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Biosynthesis and biological screening of a genetically encoded library based on the cyclotide MCoTI-I.
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"Splicing up" drug discovery. Cell-based expression and screening of genetically-encoded libraries of backbone-cyclized polypeptides.
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Discovery, structure and biological activities of cyclotides.
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The discovery and development of a natural combinatorial peptide template: the cyclotides.
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Protein side-chain dynamics and residual conformational entropy.
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Knottin cyclization: impact on structure and dynamics.
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Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides.
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Biosynthesis of a fully functional cyclotide inside living bacterial cells.
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