2-碘代苯甲酸促进的四氢-β-咔啉的室温芳构化：在 eudistomin U 的全合成中的应用。
Room-temperature aromatization of tetrahydro-β-carbolines by 2-iodoxybenzoic acid: utility in a total synthesis of eudistomin U.
机构信息
Department of Chemistry, The University of Vermont, 82 University Place, Burlington, Vermont 05405, USA.
出版信息
Org Lett. 2010 Sep 17;12(18):4086-9. doi: 10.1021/ol101688x.
Abstract
2-Iodoxybenzoic acid is a convenient reagent for the dehydrogenation of tetrahydro-β-carbolines to their aromatic forms under mild conditions. The utility of the method was demonstrated in a total synthesis of the marine indole alkaloid eudistomin U.
摘要
2-碘代苯甲酸是一种方便的试剂，可在温和条件下将四氢-β-咔啉脱氢为其芳香形式。该方法在海洋吲哚生物碱 eudistomin U 的全合成中得到了应用。
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