Barnes Kelly Anne, Howard James H, Howard Darlene V, Kenealy Laura, Vaidya Chandan J
Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Dev Neuropsychol. 2010;35(5):494-505. doi: 10.1080/87565641.2010.494750.
Attention deficit hyperactivity disorder (ADHD) is characterized by inattention, impulsivity, and hyperactivity mediated by frontal-striatal-cerebellar dysfunction. These circuits support implicit learning of perceptual-motor sequences but not visual-spatial context. ADHD and control children performed the Alternating Serial Reaction Time (ASRT) task, a measure of sequence learning, and the Contextual Cueing (CC) task, a measure of spatial contextual learning. Relative to controls, children with ADHD showed inconsistent ASRT learning but did not differ on CC learning. Thus, implicit sequence learning, a cognitive process mediated by frontal-striatal-cerebellar circuitry that is not under executive control, was atypical in ADHD.
注意力缺陷多动障碍(ADHD)的特征是注意力不集中、冲动和多动,由额叶-纹状体-小脑功能障碍介导。这些神经回路支持感知运动序列的内隐学习,但不支持视觉空间背景的学习。ADHD儿童和对照儿童进行了交替序列反应时(ASRT)任务(一种序列学习测量方法)和情境线索(CC)任务(一种空间情境学习测量方法)。与对照组相比,ADHD儿童的ASRT学习不一致,但在CC学习方面没有差异。因此,内隐序列学习是一种由额叶-纹状体-小脑神经回路介导且不受执行控制的认知过程,在ADHD中表现异常。