Dodson T B, Barton J A, Kaban L B
Department of Oral and Maxillofacial Surgery, School of Dentistry, University of California-San Francisco.
J Oral Maxillofac Surg. 1991 Aug;49(8):838-42. doi: 10.1016/0278-2391(91)90012-b.
The purpose of this study was to determine factors predictive of clinical outcome for pediatric patients with maxillofacial infections. Using linear logistic regression, four important variables, age, admission temperature, admission white blood cell count, and source of infection, were identified. Relevant study variables were abstracted from the records of all children less than 15 years old admitted to San Francisco General Hospital (SFGH) with facial infections between 1982 and 1986 (n = 105). An unfavorable clinical outcome was defined as a length of hospital stay (LOS) greater than or equal to 4 days and/or the need for an operation to resolve the infection. A favorable outcome was a LOS less than 4 days and no operation. To develop and validate the linear logistic model, the original group of patients (n = 105) was divided into index and validation sets. The index set was created by randomly selecting 80 of the original patients. The model was then applied to a validation set of the 25 remaining children. The model predicted that 13.95 of the patients in the validation set would have an unfavorable outcome. The actual number of unfavorable outcomes was 16. To further test the model's validity, a third data set was collected. It was composed of pediatric patients admitted to SFGH between January 1, 1987 and June 30, 1989 (n = 24). The model predicted that 15.99 of these patients would have an unfavorable outcome; 17 patients actually did have an unfavorable outcome.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是确定预测小儿颌面部感染临床结局的因素。通过线性逻辑回归,确定了四个重要变量:年龄、入院体温、入院时白细胞计数及感染源。相关研究变量取自1982年至1986年间入住旧金山综合医院(SFGH)的所有15岁以下面部感染儿童的记录(n = 105)。不良临床结局定义为住院时间(LOS)大于或等于4天及/或需要手术来解决感染问题。良好结局为住院时间少于4天且无需手术。为了建立和验证线性逻辑模型,将原始患者组(n = 105)分为索引集和验证集。索引集通过随机选择80名原始患者创建。然后将该模型应用于其余25名儿童的验证集。该模型预测验证集中13.95%的患者会有不良结局。不良结局的实际数量为16例。为了进一步测试该模型的有效性,收集了第三个数据集。它由1987年1月1日至1989年6月30日入住SFGH的儿科患者组成(n = 24)。该模型预测这些患者中有15.99%会有不良结局;实际上有17名患者有不良结局。(摘要截短于250字)