McCain Stephanie L, Allender Matthew C, Bohling Mark, Ramsay Edward C, Morandi Federica, Newkirk Kimberly M
Department of Small Animal Clinical Sciences, University of Tennessee, College of Veterinary Medicine, 2407 River Drive, Knoxville, Tennessee 37996, USA.
J Zoo Wildl Med. 2010 Mar;41(1):121-7. doi: 10.1638/2009-0155.1.
Two adult, spayed, female raccoons were diagnosed with thyroid neoplasia. One raccoon had a palpable, left-sided, nonfunctional thyroid adenocarcinoma which was treated with a thyroidectomy twice with local recurrence both times. After the second recurrence, pulmonary metastases were identified. A third thyroidectomy was performed, and a vascular access port was placed for administration of intravenous doxorubicin. The raccoon developed pancytopenia and became anorexic after chemotherapy, and the owner elected humane euthanasia. The second raccoon had nonpalpable, bilateral, functional follicular thyroid adenomatous hyperplasia and was treated with a right thyroidectomy and a partial left thyroidectomy, leaving behind the grossly normal portion of the left thyroid. However, the animal was still hyperthyroid after surgery and was then successfully managed with topical methimazole gel. Thyroid pathology has been documented in raccoons in Europe, but is not reported in the United States. Thyroid neoplasia in raccoons can occur as a nonfunctional adenocarcinoma, as is commonly reported in dogs, or as a functional adenoma, as is commonly reported in cats. Raccoons with adenocarcinomas should be evaluated for pulmonary metastasis. Methimazole gel may be a viable treatment option for raccoons with hyperthyroidism.
两只成年、已绝育的雌性浣熊被诊断出患有甲状腺肿瘤。一只浣熊可摸到左侧有一个无功能的甲状腺腺癌，接受了两次甲状腺切除术，但两次均出现局部复发。第二次复发后，发现有肺转移。于是进行了第三次甲状腺切除术，并放置了一个血管通路端口用于静脉注射阿霉素。这只浣熊在化疗后出现全血细胞减少并厌食，主人选择了安乐死。第二只浣熊双侧有不可触及的功能性滤泡性甲状腺腺瘤样增生，接受了右侧甲状腺切除术和左侧部分甲状腺切除术，留下了左侧甲状腺外观正常的部分。然而，这只动物术后仍有甲状腺功能亢进，随后用甲巯咪唑凝胶局部给药成功控制住病情。欧洲已有浣熊甲状腺病变的记录，但美国尚未见报道。浣熊的甲状腺肿瘤可以表现为无功能腺癌，这在犬类中较为常见，也可以表现为功能性腺瘤，这在猫类中较为常见。患有腺癌的浣熊应评估是否有肺转移。甲巯咪唑凝胶可能是治疗甲状腺功能亢进浣熊的一个可行选择。
