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成年人创伤性脑损伤的发生率——如何分类轻度病例?

The incidence of traumatic brain injury in an adult population--how to classify mild cases?

机构信息

Department of Neurosciences and Rehabilitation, Tampere University Hospital, Tampere, Finland.

出版信息

Eur J Neurol. 2011 Mar;18(3):460-4. doi: 10.1111/j.1468-1331.2010.03179.x. Epub 2010 Aug 16.

DOI:10.1111/j.1468-1331.2010.03179.x
PMID:20722703
Abstract

BACKGROUND

The incidence of traumatic brain injury (TBI) varies considerably between reports mainly because of variable methods used in recruiting of cases and especially in defining mild TBI. This study was carried out to evaluate the incidence in a given population according to published criteria for mild TBIs.

METHODS

All cases with symptoms of brain injury after a head trauma were collected from the health centres serving a defined population in South East Finland and from the one hospital taking care of all corresponding TBI cases. After reviewing the health records, the author classified the TBIs according to the guidelines of European Federation of Neurological Societies (EFNS).

RESULTS

A total of 370 patients were enrolled. The total crude annual incidence rate was 221 per 100.000 (95% CI: 176-265). A mild TBI was defined in 71% of the patients. According to the EFNS criteria, one-third of them should be classified only with head traumas because of the lack of either loss consciousness (LOC) or post-traumatic amnesia (PTA). This would reduce the total crude incidence rate to 137 per 100.000(95% CI: 101-172), an effect of the same magnitude as excluding mild TBIs treated out of hospital.

CONCLUSIONS

The incidence rate falls within the wide range of previous published figures. Use of LOC or PTA as a criterion for mild TBI affects the incidence rate considerably as does the exclusion of mild cases treated out of hospital.

摘要

背景

创伤性脑损伤(TBI)的发病率在不同报告之间差异很大,主要是由于病例招募方法不同,尤其是轻度 TBI 的定义不同。本研究旨在根据已发表的轻度 TBI 标准评估特定人群中的发病率。

方法

从服务于芬兰东南部特定人群的健康中心和负责所有相应 TBI 病例的一家医院收集所有头部外伤后出现脑损伤症状的病例。在审查健康记录后,作者根据欧洲神经病学联合会(EFNS)的指南对 TBI 进行分类。

结果

共纳入 370 例患者。总粗发病率为 221/100000(95%CI:176-265)。71%的患者被诊断为轻度 TBI。根据 EFNS 标准,由于缺乏意识丧失(LOC)或创伤后遗忘(PTA),其中三分之一的患者仅因头部外伤而被分类。这将使总粗发病率降至 137/100000(95%CI:101-172),与排除院外治疗的轻度 TBI 相同。

结论

发病率处于先前发表数据的广泛范围内。使用 LOC 或 PTA 作为轻度 TBI 的标准会极大地影响发病率,而排除院外治疗的轻度病例也会影响发病率。

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