Kundu Mrinmoy, Shet Vallabh, Janjua Tariq, Moscote Luis Rafael
Institute of Medical Sciences and SUM Hospital, Bhubaneswar, India.
Bangalore Medical College and Research Institute, Bangalore, India.
Acta Neurol Belg. 2025 Jun;125(3):635-644. doi: 10.1007/s13760-024-02691-x. Epub 2024 Dec 9.
Traumatic brain injury (TBI) is a leading cause of death and disability throughout the world. Despite significant advances in medical care, many TBI survivors continue to have cognitive, physical, and psychological deficits that have a significant impact on their quality of life. Neuromodulation techniques, which use electrical or magnetic stimulation to modulate brain activity, have shown promise in the treatment of TBI symptoms. The purpose of this narrative review is to provide an overview of the current state of neuromodulation techniques for TBI, such as transcranial magnetic stimulation, transcranial direct current stimulation, deep brain stimulation, and vagus nerve stimulation. This review summarizes the evidence for using these techniques, as well as their potential mechanisms of action and limitations. Additionally, the review discusses future research directions in this field, as well as the possibility of combining neuromodulation techniques with other interventions to improve outcomes for TBI patients.
创伤性脑损伤(TBI)是全球死亡和残疾的主要原因。尽管医疗护理取得了重大进展,但许多TBI幸存者仍然存在认知、身体和心理缺陷,这些缺陷对他们的生活质量有重大影响。神经调节技术利用电刺激或磁刺激来调节大脑活动,已显示出在治疗TBI症状方面的前景。本叙述性综述的目的是概述用于TBI的神经调节技术的现状,如经颅磁刺激、经颅直流电刺激、深部脑刺激和迷走神经刺激。本综述总结了使用这些技术的证据,以及它们潜在的作用机制和局限性。此外,该综述还讨论了该领域未来的研究方向,以及将神经调节技术与其他干预措施相结合以改善TBI患者预后的可能性。