Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
J Sex Med. 2011 Feb;8(2):549-59. doi: 10.1111/j.1743-6109.2010.01988.x. Epub 2010 Aug 16.
With the population of cancer survivors nearing 12 million, an ever-increasing number of women will face vaginal health issues related to their disease and/or treatment. Abrupt menopause triggered by cancer treatment, for example, can cause intense and prolonged estrogen deprivation symptoms, including vaginal dryness and discomfort. Simple strategies to promote vaginal health are available.
To provide a comprehensive overview of vaginal health issues caused by estrogen deprivation in female cancer patients/survivors and provide recommendations to identify, treat, and promote vaginal health.
We describe a treatment algorithm, based on scientific literature and supported by clinical experience, found to be effective in treating these patients at two major cancer centers. We also provide examples of handouts for patient education on vaginal health promotion.
Evidence-based medicine and psychosocial literature, in addition to clinical experience at two major cancer centers.
Simple, non-hormonal interventions for sexual dysfunction are often overlooked. Several studies show that education on vaginal lubricants, moisturizers, and dilator use (as needed) can decrease the morbidity of vaginal atrophy. These studies also provide support for our clinical treatment recommendations. Our goal in this article is to increase awareness of these strategies and to provide assistance to general gynecologists and oncologists caring for cancer patients and survivors.
Dedicating a small amount of time to educate female cancer survivors about methods to promote vaginal health can result in the reduction or elimination of vaginal discomfort. Non-hormonal vaginal health strategies often appear sufficient to remedy these issues. However, large randomized trials are needed, varying the format and components of the treatment program and exploring efficacy in various groups of female cancer survivors.
随着癌症幸存者人数接近 1200 万,越来越多的女性将面临与疾病和/或治疗相关的阴道健康问题。例如,癌症治疗引发的突然绝经会导致强烈和持久的雌激素缺乏症状,包括阴道干燥和不适。促进阴道健康的简单策略是可用的。
全面概述女性癌症患者/幸存者因雌激素缺乏引起的阴道健康问题,并提供识别、治疗和促进阴道健康的建议。
我们描述了一种治疗算法,该算法基于科学文献,并得到了两个主要癌症中心的临床经验支持。我们还提供了促进阴道健康促进患者教育的讲义示例。
循证医学和社会心理文献,以及两个主要癌症中心的临床经验。
性性功能障碍的简单非激素干预措施往往被忽视。几项研究表明,阴道润滑剂、保湿剂和扩张器使用(视需要)的教育可以降低阴道萎缩的发病率。这些研究也为我们的临床治疗建议提供了支持。我们在本文中的目标是提高对这些策略的认识,并为治疗癌症患者和幸存者的普通妇科医生和肿瘤学家提供帮助。
花一点时间教育女性癌症幸存者促进阴道健康的方法,可以减少或消除阴道不适。非激素阴道健康策略通常足以解决这些问题。然而,需要进行大型随机试验,改变治疗方案的形式和组成,并探索各种女性癌症幸存者群体的疗效。