David Geffen School of Medicine and Cousin's Center for Psychoneuroimmunology, University of California at Los Angeles, Los Angeles, California, USA.
J Am Geriatr Soc. 2010 May;58(5):829-36. doi: 10.1111/j.1532-5415.2010.02815.x.
To describe sleep patterns in older adults living in assisted living facilities (ALFs) and to explore the relationship between sleep disturbance and quality of life, functional status, and depression over 6 months of follow-up.
Prospective, observational cohort study.
Eighteen ALFs in the Los Angeles area.
One hundred twenty-one ALF residents aged 65 and older (mean age 85.3, 86% female, 88% non-Hispanic white).
Data were collected at baseline and 3 and 6 months after enrollment. Data collected were demographics, physical and cognitive functioning, depression, quality of life, comorbidities, medications, and subjective (i.e., questionnaires) and objective (i.e., 3 days and nights of wrist actigraphy) measures of sleep.
Sixty-five percent of participants reported clinically significant sleep disturbance on the Pittsburgh Sleep Quality Index, and objective wrist actigraphy confirmed poor sleep quality. In regression analyses including sleep variables and other predictors, more self-reported sleep disturbance at baseline was associated with worse health-related quality of life (Medical Outcomes Study 12-item Short Form Survey Mental Component Summary score) and worse depressive symptoms five-item Geriatric Depression Scale at follow-up. Worse nighttime sleep (according to actigraphy) at baseline was associated with worse activities of daily living functioning and more depressive symptoms at follow-up.
Sleep disturbance is common in older ALF residents, and poor sleep is associated with declining functional status and quality of life and greater depression over 6 months of follow-up. Studies are needed to determine whether improving sleep in ALF residents will result in improvements in these outcomes. Well-established treatments should be adapted for use in ALFs and systematically evaluated in future research.
描述居住在辅助生活设施(ALF)中的老年人的睡眠模式,并探讨睡眠障碍与生活质量、功能状态和抑郁在 6 个月随访期间的关系。
前瞻性观察队列研究。
洛杉矶地区的 18 个 ALF。
121 名年龄在 65 岁及以上的 ALF 居民(平均年龄 85.3 岁,86%为女性,88%为非西班牙裔白人)。
在入组时、入组后 3 个月和 6 个月收集数据。收集的数据包括人口统计学、身体和认知功能、抑郁、生活质量、合并症、药物以及睡眠的主观(即问卷)和客观(即 3 天和 3 夜腕部活动记录仪)测量。
65%的参与者报告匹兹堡睡眠质量指数存在临床显著的睡眠障碍,客观腕部活动记录仪证实睡眠质量差。在包括睡眠变量和其他预测因素的回归分析中,基线时自我报告的睡眠障碍越多,与健康相关的生活质量(医疗结局研究 12 项简短形式调查精神成分综合评分)和随访时的抑郁症状五项老年抑郁量表越差相关。基线时夜间睡眠较差(根据活动记录仪)与随访时日常生活活动功能较差和抑郁症状较多相关。
睡眠障碍在老年 ALF 居民中很常见,睡眠质量差与功能状态和生活质量下降以及 6 个月随访期间抑郁加重有关。需要研究改善 ALF 居民的睡眠是否会改善这些结果。应针对 ALF 患者调整既定的治疗方法,并在未来的研究中进行系统评估。