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睡眠心脏健康研究中的主观和客观睡眠质量与衰老

Subjective and objective sleep quality and aging in the sleep heart health study.

作者信息

Unruh Mark L, Redline Susan, An Ming-Wen, Buysse Daniel J, Nieto F Javier, Yeh Jeun-Liang, Newman Anne B

机构信息

Renal-Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, USA.

出版信息

J Am Geriatr Soc. 2008 Jul;56(7):1218-27. doi: 10.1111/j.1532-5415.2008.01755.x. Epub 2008 May 14.

DOI:10.1111/j.1532-5415.2008.01755.x
PMID:18482295
Abstract

OBJECTIVES

To examine the extent to which subjective and objective sleep quality are related to age independent of chronic health conditions.

DESIGN

Cross-sectional study.

SETTING

The Sleep Heart Health Study (SHHS) is a multicenter study designed to determine the cardiovascular consequences and the natural history of sleep disordered breathing.

PARTICIPANTS

Five thousand four hundred seven community-dwelling adults who participated in the SHHS (mean age 63, range 45-99; 52% women).

MEASUREMENTS

Unattended home polysomnography (PSG) and sleep questionnaires.

RESULTS

Older age was associated with shorter sleep time, diminished sleep efficiency, and more arousals in men and women. In men, age was independently associated with more Stage 1 and Stage 2 sleep and less slow-wave (Stage 3 to 4) and rapid eye movement sleep. In women, older age was less strongly associated according to linear trend with sleep stage. Conversely, poor subjective sleep quality was not associated with older age in men, but older women had more trouble falling asleep, and there was a trend toward older women having more problems with waking up during the night and waking up too early. Associations between self-report and directly measured sleep time and sleep latency were low to moderate across age groups (correlation coefficient=0.06-0.32).

CONCLUSION

Older age was more strongly associated with poorer sleep according to PSG in men than women, yet the subjective report of poor sleep with older age was stronger in women. The higher prevalence of chronic health conditions, including sleep apnea, in older adults did not explain changes of sleep parameters with aging and age-sex differences in these relationships.

摘要

目的

探讨主观和客观睡眠质量与年龄的关联程度,且不受慢性健康状况影响。

设计

横断面研究。

背景

睡眠心脏健康研究(SHHS)是一项多中心研究,旨在确定睡眠呼吸障碍的心血管后果及自然病程。

参与者

5407名参与SHHS的社区居住成年人(平均年龄63岁,范围45 - 99岁;52%为女性)。

测量方法

无人值守的家庭多导睡眠图(PSG)和睡眠问卷。

结果

年龄较大与睡眠时间较短、睡眠效率降低以及男性和女性的觉醒次数增多相关。在男性中,年龄独立与更多的1期和2期睡眠以及更少的慢波(3至4期)和快速眼动睡眠相关。在女性中,根据线性趋势,年龄与睡眠阶段的关联较弱。相反,男性主观睡眠质量差与年龄无关,但老年女性入睡困难更多,且有趋势表明老年女性夜间醒来和过早醒来的问题更多。各年龄组自我报告与直接测量的睡眠时间和睡眠潜伏期之间的关联低至中等(相关系数 = 0.06 - 0.32)。

结论

根据PSG,年龄较大在男性中比女性更强烈地与较差的睡眠相关,但女性中年龄较大时睡眠差的主观报告更强。老年人中慢性健康状况(包括睡眠呼吸暂停)的较高患病率并不能解释睡眠参数随年龄的变化以及这些关系中的年龄 - 性别差异。

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