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Cellular strategies for regulating DNA supercoiling: a single-molecule perspective.调控 DNA 超螺旋的细胞策略：单分子视角。
Cell. 2010 Aug 20;142(4):519-30. doi: 10.1016/j.cell.2010.08.001.
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Control of bacterial DNA supercoiling.细菌DNA超螺旋的调控
Mol Microbiol. 1992 Feb;6(4):425-33. doi: 10.1111/j.1365-2958.1992.tb01486.x.
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[DNA supercoiling and topoisomerases in Escherichia coli].[大肠杆菌中的DNA超螺旋与拓扑异构酶]
Rev Latinoam Microbiol. 1995 Jul-Sep;37(3):291-304.
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A multiscale dynamic model of DNA supercoil relaxation by topoisomerase IB.拓扑异构酶 IB 介导的 DNA 超螺旋松弛的多尺度动力学模型。
Biophys J. 2011 Apr 20;100(8):2016-23. doi: 10.1016/j.bpj.2011.03.003.
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Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation.人类拓扑异构酶I中DNA围绕完整链的旋转意味着正负超螺旋松弛的不同机制。
Nucleic Acids Res. 2005 Nov 27;33(20):6621-34. doi: 10.1093/nar/gki935. Print 2005.
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DNA supercoiling during ATP-dependent DNA translocation by the type I restriction enzyme EcoAI.I型限制酶EcoAI在ATP依赖的DNA转位过程中的DNA超螺旋化
J Mol Biol. 2000 Jan 28;295(4):1089-99. doi: 10.1006/jmbi.1999.3414.
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Chromatin Architectural Factors as Safeguards against Excessive Supercoiling during DNA Replication.染色质结构因素可防止 DNA 复制时过度超螺旋化。
Int J Mol Sci. 2020 Jun 24;21(12):4504. doi: 10.3390/ijms21124504.
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Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I.大肠杆菌拓扑异构酶I抑制超负DNA超螺旋的结构基础。
Nucleic Acids Res. 2015 Dec 15;43(22):11031-46. doi: 10.1093/nar/gkv1073. Epub 2015 Oct 20.
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PICH and TOP3A cooperate to induce positive DNA supercoiling.PICH 和 TOP3A 合作诱导正 DNA 超螺旋。
Nat Struct Mol Biol. 2019 Apr;26(4):267-274. doi: 10.1038/s41594-019-0201-6. Epub 2019 Apr 1.
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Roles of topoisomerases in maintaining steady-state DNA supercoiling in Escherichia coli.拓扑异构酶在维持大肠杆菌稳态DNA超螺旋中的作用。
J Biol Chem. 2000 Mar 17;275(11):8103-13. doi: 10.1074/jbc.275.11.8103.
引用本文的文献
1
Real-time imaging of rotation during synthesis by the replisome.复制体在合成过程中旋转的实时成像。
bioRxiv. 2025 Apr 7:2025.04.01.646591. doi: 10.1101/2025.04.01.646591.
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High-Resolution Genome-Wide Maps Reveal Widespread Presence of Torsional Insulation.高分辨率全基因组图谱揭示了扭转绝缘的广泛存在。
bioRxiv. 2025 Jan 4:2024.10.11.617876. doi: 10.1101/2024.10.11.617876.
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RNA polymerase collisions and their role in transcription.RNA 聚合酶碰撞及其在转录中的作用。
Transcription. 2024 Feb-Apr;15(1-2):38-47. doi: 10.1080/21541264.2024.2316972. Epub 2024 Feb 15.
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Supercoiling-dependent DNA binding: quantitative modeling and applications to bulk and single-molecule experiments.超螺旋依赖的 DNA 结合：定量建模及其在体和单分子实验中的应用。
Nucleic Acids Res. 2024 Jan 11;52(1):59-72. doi: 10.1093/nar/gkad1055.
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Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells.二苯并二碲的抗癌活性及其对人结肠癌细胞 HCT116 中 DNA 拓扑异构酶 I 的毒害作用。
Oncotarget. 2023 Jun 21;14:637-649. doi: 10.18632/oncotarget.28465.
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DNA fluctuations reveal the size and dynamics of topological domains.DNA波动揭示了拓扑结构域的大小和动态变化。
PNAS Nexus. 2022 Nov 22;1(5):pgac268. doi: 10.1093/pnasnexus/pgac268. eCollection 2022 Nov.
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Multi-Layered Regulations on the Chromatin Architectures: Establishing the Tight and Specific Responses of Fission Yeast Gene Transcription.多层次的染色质结构调控：建立裂殖酵母基因转录的紧密和特异性反应。
Biomolecules. 2022 Nov 5;12(11):1642. doi: 10.3390/biom12111642.
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Psoralen mapping reveals a bacterial genome supercoiling landscape dominated by transcription.补骨脂素作图揭示了转录主导的细菌基因组超螺旋景观。
Nucleic Acids Res. 2022 May 6;50(8):4436-4449. doi: 10.1093/nar/gkac244.
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Two-phase dynamics of DNA supercoiling based on DNA polymer physics.基于 DNA 聚合物理的 DNA 超螺旋的两相动力学。
Biophys J. 2022 Feb 15;121(4):658-669. doi: 10.1016/j.bpj.2022.01.001. Epub 2022 Jan 10.
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DNA Supercoiling Drives a Transition between Collective Modes of Gene Synthesis.DNA 超螺旋驱动基因合成的集体模式之间的转变。
Phys Rev Lett. 2021 Nov 19;127(21):218101. doi: 10.1103/PhysRevLett.127.218101.
本文引用的文献
1
Insights from the structure of a smallpox virus topoisomerase-DNA transition state mimic.从小天花病毒拓扑异构酶-DNA 转变态模拟物的结构中得到的认识。
Structure. 2010 Jan 13;18(1):127-37. doi: 10.1016/j.str.2009.10.020.
2
Mechanisms of chiral discrimination by topoisomerase IV.拓扑异构酶IV的手性识别机制。
Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6986-91. doi: 10.1073/pnas.0900574106. Epub 2009 Apr 9.
3
DNA topoisomerases: harnessing and constraining energy to govern chromosome topology.DNA拓扑异构酶：利用和控制能量以调控染色体拓扑结构
Q Rev Biophys. 2008 Feb;41(1):41-101. doi: 10.1017/S003358350800468X.
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Single-molecule approach to molecular biology in living bacterial cells.活细菌细胞分子生物学的单分子方法。
Annu Rev Biophys. 2008;37:417-44. doi: 10.1146/annurev.biophys.37.092607.174640.
5
Internal dynamics of superhelical DNA.超螺旋DNA的内部动力学
Phys Rev Lett. 2008 Mar 7;100(9):098102. doi: 10.1103/PhysRevLett.100.098102. Epub 2008 Mar 6.
6
Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms.完整的II型DNA拓扑异构酶的晶体结构：对DNA转移机制的见解
Structure. 2008 Mar;16(3):360-70. doi: 10.1016/j.str.2007.12.020.
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Three-dimensional magneto-optic trap for micro-object manipulation.用于微物体操纵的三维磁光阱
Opt Lett. 2001 Sep 1;26(17):1359-61. doi: 10.1364/ol.26.001359.
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Topoisomerase V relaxes supercoiled DNA by a constrained swiveling mechanism.拓扑异构酶V通过一种受限旋转机制来松弛超螺旋DNA。
Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14670-5. doi: 10.1073/pnas.0701989104. Epub 2007 Sep 5.
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Fast dynamics of supercoiled DNA revealed by single-molecule experiments.单分子实验揭示的超螺旋DNA的快速动力学
Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):11957-62. doi: 10.1073/pnas.0700333104. Epub 2007 Jul 10.
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Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI.拓扑异构酶VI的全酶组装及ATP介导的构象动力学
Nat Struct Mol Biol. 2007 Jul;14(7):611-9. doi: 10.1038/nsmb1264. Epub 2007 Jul 1.
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