Shope S R, Schiemann D A
Department of Microbiology, Montana State University, Bozeman 59717.
J Med Microbiol. 1991 Jul;35(1):53-9. doi: 10.1099/00222615-35-1-53.
Mice immunised by drinking water containing an Aro- mutant strain of Salmonella typhimurium produced intestinal IgA antibodies after a memory response which was demonstrated by measuring copro-antibodies. After oral challenge with a virulent strain of S. typhimurium, foster mouse pups placed with immunised mothers survived longer than control pups held with non-immunised mothers.
用含有鼠伤寒沙门氏菌Aro-突变株的饮水免疫的小鼠,在通过检测粪抗体证实的记忆反应后产生了肠道IgA抗体。在用鼠伤寒沙门氏菌强毒株进行口服攻击后,与免疫母鼠待在一起的寄养幼鼠比与未免疫母鼠待在一起的对照幼鼠存活时间更长。