Department of Ophthalmology, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
J Neuroophthalmol. 2010 Sep;30(3):266-7. doi: 10.1097/WNO.0b013e3181e08ee7.
We describe a case of ocular neuromyotonia (ONM) following concurrent chemoradiotherapy for nasopharyngeal carcinoma (NPC). During an episode of neuromyotonia, the patient developed involuntary contraction of the left lateral rectus muscle and globe retraction with down-shoot movement in the left eye. In the quiescent period, ocular motor examination revealed a partial left sixth nerve palsy. While diplopic complaints in patients with NPC raise suspicion of tumor recurrence or radiation-related cranial neuropathy, ONM must also be kept in the differential diagnosis.
我们描述了一例鼻咽癌(NPC)同期放化疗后出现的眼肌肌强直性(ONM)。在肌强直性发作期间,患者出现左眼外直肌不自主收缩和眼球回缩,伴有向下的眼球运动。在静止期,眼球运动检查显示左侧第六脑神经部分麻痹。虽然 NPC 患者出现复视症状会引起对肿瘤复发或放射性颅神经病的怀疑,但在鉴别诊断中也必须考虑到 ONM。