Trauma Centre Brabant, St Elisabeth Hospital Tilburg, Tilburg, The Netherlands.
Br J Surg. 2010 Dec;97(12):1805-13. doi: 10.1002/bjs.7216. Epub 2010 Aug 19.
There is growing demand for a simple accurate scoring model to evaluate the quality of trauma care. This study compared different trauma survival prediction models with regard to their performance in different trauma populations.
The probability of survival for 10,777 trauma patients admitted to hospital was calculated using the formulas of the following models: the Major Trauma Outcome Study (MTOS), the Trauma Audit and Research Network (TARN) and the Base Excess Injury Severity Scale (BISS). Updated coefficients were calculated by logistic regression analysis based on a Dutch data set. Different models were compared for several subsets of patients, according to age and injury type and severity, using the area under the receiver operating characteristic (ROC) curve (AUC). Calibration for the updated models was presented graphically.
Most of the models had an AUC exceeding 0·8. For the total population, the TARN Ps07 model with updated coefficients had the highest AUC (0·924); for the subset of patients in whom all parameters were available, the BISS model including the Glasgow Coma Scale had the highest AUC (0·909). All of the models had high discriminative power for patients aged less than 55 years. However, in older or intubated patients and in those with severe head injuries the discriminative power of the models dropped. The TARN model showed the best accuracy.
The investigated models predict mortality fairly accurately in a Dutch trauma population. However, the accuracy of the models depends greatly on the patients included. Severe head injuries and greater age are likely to lead to a decrease in the accuracy of survival prediction.
人们越来越需要一种简单而准确的评分模型来评估创伤救治的质量。本研究比较了不同创伤生存预测模型在不同创伤人群中的表现。
使用以下模型的公式计算了 10777 例住院创伤患者的生存概率:重大创伤结局研究(MTOS)、创伤审核与研究网络(TARN)和基础过剩损伤严重度评分(BISS)。根据荷兰数据集,通过逻辑回归分析计算了更新后的系数。根据年龄和损伤类型和严重程度,对不同模型进行了比较,使用受试者工作特征(ROC)曲线下面积(AUC)。更新后的模型的校准通过图形呈现。
大多数模型的 AUC 超过 0.8。对于总人口,具有更新系数的 TARN Ps07 模型具有最高的 AUC(0.924);对于所有参数都可用的患者亚组,包括格拉斯哥昏迷量表的 BISS 模型具有最高的 AUC(0.909)。所有模型对于年龄小于 55 岁的患者均具有较高的鉴别能力。然而,在年龄较大或需要插管的患者以及严重颅脑损伤患者中,模型的鉴别能力下降。TARN 模型显示出最佳的准确性。
在荷兰创伤人群中,所研究的模型可以相当准确地预测死亡率。然而,模型的准确性在很大程度上取决于所包括的患者。严重颅脑损伤和年龄较大可能会导致生存预测准确性下降。