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卢戈氏碘可识别同步浸润性癌——开展临床试验的时候到了。

Lugol's iodine identifies synchronous invasive carcinoma--time for a clinical trial.

作者信息

Kanatas A N, Jenkins G W, Sutton D, McCaul J A

机构信息

Maxillofacial Unit, Bradford Teaching Hospitals NHS Foundation Trust, Bradford BD5 0NA, United Kingdom.

出版信息

Br J Oral Maxillofac Surg. 2011 Jul;49(5):409-11. doi: 10.1016/j.bjoms.2010.07.013. Epub 2010 Aug 21.

DOI:10.1016/j.bjoms.2010.07.013
PMID:20727630
Abstract

Lugol's iodine is currently under investigation as a technique to detect dysplasia, carcinoma in situ and invasive carcinoma at resection margins, plus further afield. Lugol's iodine is inexpensive and easy to use. We present two cases where the technique revealed abnormal mucosa (one carcinoma, one squamous cell carcinoma in situ) at distant sites from the tumour being treated within oral cavity and oropharynx.

摘要

目前正在研究使用卢戈氏碘作为一种检测切除边缘以及更远部位发育异常、原位癌和浸润性癌的技术。卢戈氏碘价格低廉且易于使用。我们报告两例病例,该技术在口腔和口咽正在治疗的肿瘤远处部位发现了异常黏膜(一例为癌,一例为原位鳞状细胞癌)。

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Lugol's iodine identifies synchronous invasive carcinoma--time for a clinical trial.卢戈氏碘可识别同步浸润性癌——开展临床试验的时候到了。
Br J Oral Maxillofac Surg. 2011 Jul;49(5):409-11. doi: 10.1016/j.bjoms.2010.07.013. Epub 2010 Aug 21.
2
Use of Lugol's iodine in the resection of oral and oropharyngeal squamous cell carcinoma.卢戈氏碘在口腔及口咽鳞状细胞癌切除术中的应用。
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LIHNCS - Lugol's iodine in head and neck cancer surgery: a multicentre, randomised controlled trial assessing the effectiveness of Lugol's iodine to assist excision of moderate dysplasia, severe dysplasia and carcinoma in situ at mucosal resection margins of oral and oropharyngeal squamous cell carcinoma: study protocol for a randomised controlled trial.LIHNCS - 卢戈氏碘在头颈癌手术中的应用:一项多中心随机对照试验,评估卢戈氏碘在口腔和口咽鳞状细胞癌黏膜切除边缘辅助切除中度发育异常、重度发育异常和原位癌的有效性:一项随机对照试验的研究方案
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Clinical evaluation of Lugol's iodine staining in the treatment of stage I-II squamous cell carcinoma of the tongue.卢戈氏碘染色在治疗Ⅰ-Ⅱ期舌鳞癌中的临床评价。
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Clinical relevance of the utilization of vital Lugol's iodine staining in detection and diagnosis of oral cancer and dysplasia.在口腔癌及发育异常检测与诊断中使用活性卢戈氏碘染色的临床相关性。
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Transoral laser resection with staged discontinuous neck dissection for oral cavity and oropharynx squamous cell carcinoma.经口激光切除术联合分期间断性颈部清扫术治疗口腔及口咽鳞状细胞癌
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The clinicopathologic significance of small areas unstained by Lugol's iodine in the mucosa surrounding resected esophageal carcinoma: an analysis of 147 cases.切除的食管癌周围黏膜中未被卢戈氏碘染色的小区域的临床病理意义:147例分析
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Long-term results in treating squamous cell carcinoma of the lip, oral cavity, and oropharynx.唇部、口腔和口咽鳞状细胞癌的长期治疗结果。
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Application of narrow band imaging and Lugol's iodine staining in screening for nasopharyngeal carcinoma.窄带成像技术及卢戈氏碘染色在鼻咽癌筛查中的应用。
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