Department of Pathology, University of Agriculture, Faisalabad, Pakistan.
Food Chem Toxicol. 2010 Dec;48(12):3304-7. doi: 10.1016/j.fct.2010.08.016. Epub 2010 Aug 20.
This study describes the effect of dietary levels of aflatoxin B1 (AFB1) and age of the birds upon the residue level in liver and muscles of broiler chicks. In three different experiments broiler chicks of 7, 14 and 28 days of age were kept for 7 days on contaminated rations having 1600, 3200 and 6400 μg/kg AFB1. AFB1 residues were detected earlier in younger birds and those fed high AFB1 dietary levels. The highest residue levels in liver and muscles of young chicks fed 6400 μg/kg AFB1 was 6.97±0.08 and 3.27±0.05 ng/g, respectively. Maximum residue concentration was high in birds of young age and those kept on high AFB1 ration. After withdrawal of AF contaminated rations, residues clearance was slow and AFB1 was detectable in liver and muscles of birds for longer duration in younger birds and those fed high AFB1 dietary levels. AFB1 residues in poultry tissues may buildup to high levels in areas with no regulatory limits on AFB1 levels of poultry feed and may pose a risk to consumers health.
本研究描述了黄曲霉毒素 B1（AFB1）的饮食水平和鸟类年龄对肉鸡雏鸡肝脏和肌肉中残留水平的影响。在三个不同的实验中，7、14 和 28 日龄的肉鸡雏鸡分别在含有 1600、3200 和 6400μg/kg AFB1 的污染日粮上饲养 7 天。在年龄较小的鸟类和喂食高 AFB1 饮食水平的鸟类中，更早地检测到 AFB1 残留。在喂食 6400μg/kg AFB1 的年轻雏鸡的肝脏和肌肉中，最高残留水平分别为 6.97±0.08 和 3.27±0.05ng/g。在年轻鸟类和喂食高 AFB1 日粮的鸟类中，最高残留浓度较高。在停止摄入受 AFB 污染的日粮后，残留清除速度较慢，在年龄较小的鸟类和喂食高 AFB1 饮食水平的鸟类中，肝脏和肌肉中仍能检测到 AFB1 残留。在没有对禽饲料 AFB1 水平进行监管的地区，禽组织中的 AFB1 残留可能会积聚到高水平，从而对消费者的健康构成威胁。
