Takenaka A, Ueda S, Terao K, Takenaka O
Department of Biochemistry, Kyoto University, Aichi, Japan.
Mol Biol Evol. 1991 May;8(3):320-6. doi: 10.1093/oxfordjournals.molbev.a040652.
Alpha-globin genes in crab-eating macaques were found to be triplicated at high frequencies according to restriction-enzyme comparisons. The frequencies of triplicated alpha-globin genes in macaques originally from Malaysia and Indonesia were 0.432 and 0.275, respectively, while no triplication was found in individuals from either the Philippines or northern and central Thailand. Quadruplicated alpha-globin genes were also observed, at frequencies of 0.045 (Malaysia), 0.075 (Indonesia), and 0.021 (the Philippines). A single locus was detected in only one of 40 chromosomes from Indonesia (frequency 0.025).
根据限制性内切酶比较发现,食蟹猕猴的α-珠蛋白基因以高频率发生三倍体化。最初来自马来西亚和印度尼西亚的猕猴中,α-珠蛋白基因三倍体化的频率分别为0.432和0.275,而在来自菲律宾或泰国北部和中部的个体中未发现三倍体化现象。还观察到了四倍体化的α-珠蛋白基因,频率分别为0.045(马来西亚)、0.075(印度尼西亚)和0.021(菲律宾)。在来自印度尼西亚的40条染色体中,仅在其中一条上检测到单个位点(频率为0.025)。