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正电子发射断层扫描(PET)在脑肿瘤放射治疗计划中的应用。

PET for radiation treatment planning of brain tumours.

机构信息

Department of Radiation Oncology, University of Freiburg, Germany.

出版信息

Radiother Oncol. 2010 Sep;96(3):325-7. doi: 10.1016/j.radonc.2010.08.001. Epub 2010 Aug 20.

DOI:10.1016/j.radonc.2010.08.001
PMID:20728952
Abstract

AA-PET (MET-PET and FET-PET) can be used for gross tumour volume (GTV) delineation in brain gliomas and for the differentiation between treatment-related changes (pseudo-progression, pseudo-regression) and residual/recurrent tumour. There are some data showing that MET-PET and (DOTATOC)-PET can be used for GTV delineation in meningiomas and glomus tumours. The role of PET in the visualization of the biological characteristics of the tumours: proliferation (FLT-PET), hypoxia (FMISO-PET) and angiogenesis/peptide expression (RGD-PET) should be investigated in future studies.

摘要

AA-PET(MET-PET 和 FET-PET)可用于脑胶质瘤的大体肿瘤体积(GTV)勾画,以及区分治疗相关变化(假性进展、假性缓解)和残留/复发肿瘤。有一些数据表明,MET-PET 和(DOTATOC)-PET 可用于脑膜瘤和神经鞘瘤的 GTV 勾画。在未来的研究中,应探讨 PET 在肿瘤生物学特征可视化方面的作用,如增殖(FLT-PET)、缺氧(FMISO-PET)和血管生成/肽表达(RGD-PET)。

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