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[关于补体在增强兔IgM对仙台病毒的血凝抑制活性中可能重要性的研究]

[Studies of the possible importance of complement in increasing the hemagglutination-inhibiting activity of rabbit IgM against Sendai virus].

作者信息

De Stasio A, Orsi N, Seganti L, Sinibaldi L

出版信息

Boll Ist Sieroter Milan. 1978 Mar 31;57(1):54-9.

PMID:207291
Abstract

An investigation has been carried out in order to ascertain the effect of the presence of complement on the HI antibodies of the IgM class obtained in rabbit against Sendai virus. Contrary to the results obtained by some AA. with other viruses, in this case the presence of complement in the form of fresh guinea-pig serum has not modified the HI titre. It has however been demonstrated that in the guinea-pig serum an inhibitor is present, which is active towards Sendai virus and can be identified as a 19S alpha-globulin.

摘要

为了确定补体的存在对兔体内获得的抗仙台病毒IgM类血凝抑制(HI)抗体的影响,已开展了一项研究。与一些研究人员用其他病毒所获得的结果相反,在这种情况下,新鲜豚鼠血清形式的补体的存在并未改变HI效价。然而,已经证明在豚鼠血清中存在一种抑制剂,它对仙台病毒具有活性,并且可以鉴定为19Sα球蛋白。

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