Isaeva G Sh, Efimova N G
Eksp Klin Gastroenterol. 2010(6):30-4.
The study involved 160 patients with chronic cholecystitis associated with chronic gastroduodenitis. Obtaining biopsy specimens of gastric mucosa and bile samples allowed to compare the microbial picture and the morphological structure of gastric mucosa in the same patient, to identify patterns of colonization of the stomach, 12 duodenal ulcer and gall bladder various microorganisms. At cytological examination was detected in the gall bladder G. lamblia in 47.5 +/- 3.95% of cases in the stomach--in 29.09 +/- 6.12% of cases. The frequency of H. pylori detection in biopsy of gastric mucosa amounted to 98.18 +/- 1.8% of cases, in 12-duodenum--93.75 +/- 1.9%, in the gall bladder--to 54.38 +/- 3.94%, in the bile duct--in 54.38 +/- 3.94%. It was found strict association between the detection of H. pylori and G. lamblia in the stomach--100% of H. pylori-infection combined with giardiasis. Morphological changes of gastric mucosa in the form of lymphoid infiltration detected mainly in the mixed-infection H. pylori and G. lamblia.
该研究纳入了160例患有慢性胆囊炎合并慢性胃十二指肠炎症的患者。获取胃黏膜活检标本和胆汁样本,以便比较同一患者胃黏膜的微生物情况和形态结构,确定胃、十二指肠溃疡和胆囊中各种微生物的定植模式。在细胞学检查中,在胆囊中检测到蓝氏贾第鞭毛虫的病例占47.5±3.95%,在胃中占29.09±6.12%。胃黏膜活检中幽门螺杆菌的检出率为98.18±1.8%,在十二指肠球部为93.75±1.9%,在胆囊中为54.38±3.94%,在胆管中为54.38±3.94%。发现胃中幽门螺杆菌和蓝氏贾第鞭毛虫的检出之间存在紧密关联——100%的幽门螺杆菌感染合并贾第虫病。胃黏膜的形态学改变主要表现为淋巴细胞浸润,多见于幽门螺杆菌和蓝氏贾第鞭毛虫混合感染。