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局麻药混合物对超声或手动器械洁牙时疼痛感知的影响:一项盲法随机对照试验。

Effect of eutectic mixture of local anesthetics on pain perception during scaling by ultrasonic or hand instruments: a masked randomized controlled trial.

机构信息

Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Korea.

出版信息

J Periodontol. 2011 Feb;82(2):259-66. doi: 10.1902/jop.2010.090748. Epub 2010 Aug 23.

Abstract

BACKGROUND

The aims of this study are to evaluate the efficacy of a eutectic mixture of local anesthetic (EMLA) cream on pain perception during scaling and to compare the intensities of pain provoked by hand and ultrasonic instruments.

METHODS

Forty subjects with chronic gingivitis or periodontitis were enrolled in the study. In this randomized, split-mouth, controlled, masked clinical trial, each of the four quadrants in subjects was randomly assigned to receive one of the following protocols: scaling with an ultrasonic scaler with or without the application of the EMLA cream or scaling with a Gracey curet with or without the application of the EMLA cream. Pain levels after each quadrant of scaling were assessed with a visual analog scale (VAS; 0 to 100 mm) and verbal rating score (VRS; 0 to 4). All subjects were recalled to detect any complications after 24 hours.

RESULTS

The mean VAS and VRS when EMLA cream was applied (18.39 ± 14.47 mm and 0.95 ± 0.69) were significantly lower (P <0.001 for VAS and VRS) compared to when EMLA cream was not used (26.54 ± 16.46 mm and 1.30 ± 0.75). The mean VAS and VRS of the ultrasonic scaler group (20.43 ± 16.40 mm and 0.98 ± 0.76) were significantly lower (P = 0.024 for VAS; P = 0.003 for VRS) than those of the Gracey curet group (24.50 ± 15.17 mm and 1.28 ± 0.69). None of the subjects showed adverse effects after EMLA-cream application.

CONCLUSION

Although most patients experienced limited pain during scaling, a significant reduction of pain is achieved by using EMLA cream and ultrasonic scaler.

摘要

背景

本研究旨在评估局部麻醉混合剂(EMLA 乳膏)在洁治过程中对疼痛感知的疗效,并比较手动和超声器械引起的疼痛强度。

方法

将 40 名患有慢性牙龈炎或牙周炎的受试者纳入研究。在这项随机、分侧、对照、盲法临床试验中,将每位受试者的四个象限随机分配接受以下方案之一:使用超声洁牙机或 EMLA 乳膏进行洁治,或使用 Gracey 刮治器或 EMLA 乳膏进行洁治。使用视觉模拟量表(VAS;0 至 100 毫米)和口头评分量表(VRS;0 至 4)评估每次象限洁治后的疼痛水平。所有受试者在 24 小时后回诊以检测任何并发症。

结果

应用 EMLA 乳膏时的平均 VAS 和 VRS(18.39 ± 14.47 毫米和 0.95 ± 0.69)明显低于(VAS 和 VRS 均 P <0.001)未使用 EMLA 乳膏时的 VAS 和 VRS(26.54 ± 16.46 毫米和 1.30 ± 0.75)。超声洁牙机组的平均 VAS 和 VRS(20.43 ± 16.40 毫米和 0.98 ± 0.76)明显低于(VAS 为 P = 0.024;VRS 为 P = 0.003)Gracey 刮治器组的 VAS 和 VRS(24.50 ± 15.17 毫米和 1.28 ± 0.69)。应用 EMLA 乳膏后,所有受试者均无不良反应。

结论

虽然大多数患者在洁治过程中仅感到轻度疼痛,但使用 EMLA 乳膏和超声洁牙机可显著减轻疼痛。

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