FitzGerald P M, Jankovic J, Glaze D G, Schultz R, Percy A K
Department of Neurology, Baylor College of Medicine, Houston, TX 77030.
Neurology. 1990 Feb;40(2):293-5. doi: 10.1212/wnl.40.2.293.
Extrapyramidal dysfunction is poorly characterized in Rett's syndrome, a neurodegenerative disorder in girls. We studied the motor and behavioral findings in 32 Rett's syndrome patients, 21 months to 30 years old. In addition to the typical stereotyped movements and scoliosis, other motor disturbances included bruxism, sialorrhea, ocular deviations, parkinsonian findings, dystonia, myoclonus, and athetosis. The types of movement disorders seemed to be age-related, with the hyperkinetic disorders occurring in the younger patients and the bradykinetic disorders occurring more frequently in the older patients.
锥体外系功能障碍在雷特综合征中表现不明显，雷特综合征是一种发生于女童的神经退行性疾病。我们研究了32例年龄在21个月至30岁之间的雷特综合征患者的运动和行为表现。除了典型的刻板动作和脊柱侧弯外，其他运动障碍还包括磨牙症、流涎、眼球偏斜、帕金森氏症表现、肌张力障碍、肌阵挛和手足徐动症。运动障碍的类型似乎与年龄有关，运动亢进性障碍多见于较年轻的患者，而运动迟缓性障碍在年龄较大的患者中更为常见。
