Neurology and Neurosurgery, Department of Clinical Sciences, Iowa State University, College of Veterinary Medicine, 1600 South 16th street, Ames, IA 50011-1250, USA.
Vet Clin North Am Small Anim Pract. 2010 Sep;40(5):915-27. doi: 10.1016/j.cvsm.2010.05.010.
Tumors arising from or involving the spinal cord are important considerations in animals presented for pain and limb dysfunction. Clinical signs of spinal cord dysfunction, however, are not pathognomic for neoplastic disease in most instances. Advanced magnetic resonance imaging (MRI) often accurately identifies the location and extent of abnormalities. Although some spinal neoplasms have a characteristic appearance with MRI, in other instances the abnormalities may not be readily discernable as neoplastic. Histologic diagnosis, therefore, is imperative to provide information regarding potential treatment modalities and prognosis. Histologic diagnosis is most commonly performed following surgical biopsy and is often performed in combination with surgical removal.
起源于脊髓或累及脊髓的肿瘤是出现疼痛和肢体功能障碍的动物的重要考量因素。然而,在大多数情况下,脊髓功能障碍的临床体征并非肿瘤性疾病的特征性表现。先进的磁共振成像(MRI)通常能准确识别异常的位置和范围。尽管一些脊髓肿瘤在MRI上有特征性表现,但在其他情况下,这些异常可能不容易被识别为肿瘤性病变。因此,组织学诊断对于提供有关潜在治疗方式和预后的信息至关重要。组织学诊断最常见于手术活检后进行,并且通常与手术切除联合进行。