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指甲银屑病的负担:引言。

The burden of nail psoriasis: an introduction.

机构信息

Nail Disease Center, Cannes, France.

出版信息

Dermatology. 2010;221 Suppl 1:1-5. doi: 10.1159/000316169. Epub 2010 Aug 9.

DOI:10.1159/000316169
PMID:20733309
Abstract

Nail involvement is an extremely common feature of psoriasis and affects approximately 50% of patients. Despite this, it is an often overlooked feature of the disease, and treatment tends to be focused on clearing the cutaneous component of psoriasis. Clinical manifestations of nail psoriasis are pitting, discolouration, onycholysis and subungual hyperkeratosis as well as nail plate crumbling and splinter haemorrhages. Nail psoriasis is associated with discomfort in many patients and leads to significant functional impairment and psychological stress. The often distressing appearance of affected nails impacts the patient tremendously in both work and social activities. Importantly, 80% of patients with psoriatic arthritis have nail psoriasis. This review discusses the incidence of nail psoriasis and the burden on the patient and illustrates when dermatologists are strategically placed to detect the early signs of more severe disease by promptly diagnosing and managing the nail component of psoriasis.

摘要

指甲受累是银屑病的一个极其常见的特征,大约影响 50%的患者。尽管如此,它通常是疾病中被忽视的一个特征,治疗往往侧重于清除银屑病的皮肤成分。指甲银屑病的临床表现包括凹痕、变色、甲分离和甲下过度角化,以及甲板碎裂和裂片出血。指甲银屑病在许多患者中会引起不适,导致显著的功能障碍和心理压力。受影响指甲的外观通常会给患者带来巨大的影响,无论是在工作还是社会活动中。重要的是,80%的银屑病关节炎患者有指甲银屑病。这篇综述讨论了指甲银屑病的发生率以及对患者的负担,并说明了皮肤科医生通过及时诊断和治疗银屑病的指甲成分,在发现更严重疾病的早期迹象方面具有战略地位。

相似文献

1
The burden of nail psoriasis: an introduction.指甲银屑病的负担:引言。
Dermatology. 2010;221 Suppl 1:1-5. doi: 10.1159/000316169. Epub 2010 Aug 9.
2
Approach to managing patients with nail psoriasis.指甲银屑病患者的管理方法。
J Eur Acad Dermatol Venereol. 2009 Sep;23 Suppl 1:15-21. doi: 10.1111/j.1468-3083.2009.03364.x.
3
Linear pitting and splinter haemorrhages are more commonly seen in the nails of patients with established psoriasis in comparison to psoriatic arthritis.线性凹痕和裂片样出血在已确诊的银屑病患者的指甲中比在银屑病关节炎患者中更为常见。
Dermatology. 2011;223(4):370-3. doi: 10.1159/000335571. Epub 2012 Feb 2.
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Nail psoriasis in Germany: epidemiology and burden of disease.德国甲银屑病的流行病学和疾病负担。
Br J Dermatol. 2010 Sep;163(3):580-5. doi: 10.1111/j.1365-2133.2010.09831.x. Epub 2010 Apr 28.
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Psoriasis of the nail: anatomy, pathology, clinical presentation, and a review of the literature on therapy.甲银屑病:解剖学、病理学、临床表现及治疗文献综述
J Am Acad Dermatol. 2007 Jul;57(1):1-27. doi: 10.1016/j.jaad.2005.07.073.
6
Nail psoriasis.甲银屑病
Cutis. 1992 Sep;50(3):174-8.
7
Prevalence, severity and clinical features of psoriasis in fingernails and toenails in adult patients: Italian experience.成人甲银屑病的患病率、严重程度和临床特征:意大利经验。
J Eur Acad Dermatol Venereol. 2012 Nov;26(11):1354-9. doi: 10.1111/j.1468-3083.2011.04289.x. Epub 2011 Oct 6.
8
Psoriatic nails: a prospective clinical study.银屑病指甲:一项前瞻性临床研究。
J Cutan Med Surg. 2003 Jul-Aug;7(4):317-21. doi: 10.1007/s10227-002-0143-0. Epub 2003 Jul 28.
9
Nail psoriasis: a review.甲银屑病:综述。
Am J Clin Dermatol. 2012 Dec 1;13(6):375-88. doi: 10.2165/11597000-000000000-00000.
10
Response of psoriatic nails to oral photochemotherapy.银屑病甲对口服光化学疗法的反应。
Arch Dermatol. 1980 Sep;116(9):1023-24.

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