Arnault P, Roger M
Laboratoire de Neurophysiologie, CNRS, URA 290, Faculté des Sciences, Poitiers, France.
Behav Brain Res. 1990 Dec 7;41(1):29-38. doi: 10.1016/0166-4328(90)90051-f.
In the ovariectomized, hormone-primed rat the peripeduncular area (PPA) has been reported to play a key role in sexual receptivity by integrating the sensory and endocrine inputs necessary for the elicitation of the lordosis reflex. The present study was undertaken to investigate the effect of bilateral peripeduncular lesions induced by ibotenic acid on the lordosis behavior of the normal, cyclic rat. Sexually unexperienced females received a bilateral microinjection of either ibotenic acid (n = 14; lesion group) or phosphate buffer (n = 8; sham-operated group) in the PPA. Following recovery, the receptivity expressed as the lordosis quotient was controlled in the presence of a sexually active male. The results indicate that in both groups the females display a high lordosis quotient (LQ greater than 90%). Therefore, in the cyclic female rat, the manifestation of sexual receptivity does not seem to be affected following bilateral destruction of the PPA.
在去卵巢、激素预处理的大鼠中，据报道，脚周区（PPA）通过整合引发脊柱前凸反射所需的感觉和内分泌输入，在性接受性方面发挥关键作用。本研究旨在探讨由鹅膏蕈氨酸诱导的双侧脚周区损伤对正常、处于发情周期的大鼠脊柱前凸行为的影响。未经历过性行为的雌性大鼠在脚周区接受双侧微量注射，其中一组注射鹅膏蕈氨酸（n = 14；损伤组），另一组注射磷酸盐缓冲液（n = 8；假手术组）。恢复后，在有性活跃雄性存在的情况下，以脊柱前凸商表示的接受性受到控制。结果表明，两组中的雌性大鼠均表现出较高的脊柱前凸商（LQ大于90%）。因此，在处于发情周期的雌性大鼠中，双侧脚周区破坏后，性接受性的表现似乎并未受到影响。
