School of Medicine, University of Colorado Denver, Aurora, CO, USA.
Curr Cardiol Rep. 2010 Nov;12(6):488-96. doi: 10.1007/s11886-010-0135-4.
Innate differences in gender physiology result in unique exposures, risk, and protection that are specific to women. Recognition and appreciation of these differences results in better treatment adaptations for women and better outcomes. Disparities between genders in the treatment of major cardiovascular risk factors still exist and are mostly secondary to underestimating or misunderstanding a woman's risk. Preventive therapies are less often recommended to women. Women are more likely to be diagnosed and treated for hypertension, but are less likely to reach treatment goals. High-risk women-including diabetic women-are less likely to be on lipid-lowering agents and reach a low-density lipoprotein level less than 100 mg/dL. Diabetic women are less likely to achieve a hemoglobin A(1c) level less than 7%. Through understanding these disparities, health care providers will be better able to screen female patients and institute evidence-based therapies for the prevention of cardiovascular disease.
性别生理上的先天差异导致了女性特有的暴露、风险和保护。认识和重视这些差异可以为女性提供更好的治疗适应,并带来更好的结果。在治疗主要心血管风险因素方面,性别差异仍然存在,主要是由于低估或误解女性的风险。预防性治疗方案较少推荐给女性。女性更容易被诊断和治疗高血压,但更难达到治疗目标。高危女性,包括糖尿病女性,使用降脂药物的可能性较低,低密度脂蛋白水平也低于 100mg/dL。糖尿病女性实现血红蛋白 A1c 水平低于 7%的可能性也较低。通过了解这些差异,医疗保健提供者将能够更好地为女性患者进行筛查,并为预防心血管疾病实施基于证据的治疗方案。