Christmann M, Erffa S von, Rosewich M, Rose M A, Schulze J, Zielen S
Allergologie, Pneumologie und Mukoviszidose, Zentrum für Kinder- und Jugendmedizin, Theodor-Stern-Kai 7, Frankfurt am Main.
Pneumologie. 2010 Dec;64(12):745-51. doi: 10.1055/s-0030-1255625. Epub 2010 Aug 23.
The question about the repeatability of forced expiratory manoeuvres in childhood lung function testing is of scientific and clinical interest. The following study investigated to what extent children ≥ 4 to < 7 years of age with intermittent bronchial asthma are able to produce reproducible lung function measurements on the one hand in the healthy status and on the other hand in an exacerbated status.
64 children at the age of ≥ 4 to < 7 years with intermittent preschool bronchial asthma performed lung function measurements in the healthy status and again in an exacerbated status. FEV (1) values from the measurements were analysed according to ATS/ERS guidelines concerning repeatability.
According to the new ATS/ERS guidelines 74.6 % of the children could perform at least 2, and 59.3 % could perform 3 repeatable measurements in the healthy status. In the exacerbated status this was 87.5 % and 68.8 %, respectively. There were no significant differences between the healthy and the exacerbated status and between the age groups. Compared to former repeatability criteria, children of this age group can perform significantly more reproducible measurements (p < 0.0001).
The ATS/ERS guidelines from 2007 simplify the repeatability of forced expiratory manoeuvres in children at ≥ 4 to < 7 years of age compared to the former criteria. Repeatability is not reduced in the exacerbated status. 74.6 % of children in this age group can produce repeatable lung function measurements.
儿童肺功能测试中用力呼气动作的可重复性问题具有科学和临床意义。以下研究调查了年龄在4岁及以上至7岁以下的间歇性支气管哮喘儿童在健康状态和病情加重状态下，其肺功能测量结果的可重复性程度。
64名年龄在4岁及以上至7岁以下的学龄前间歇性支气管哮喘儿童在健康状态下进行了肺功能测量，并在病情加重状态下再次进行测量。根据美国胸科学会/欧洲呼吸学会关于可重复性的指南，对测量所得的第1秒用力呼气容积（FEV₁）值进行分析。
根据新的美国胸科学会/欧洲呼吸学会指南，74.6%的儿童在健康状态下能够至少进行2次可重复测量，59.3%的儿童能够进行3次可重复测量。在病情加重状态下，这两个比例分别为87.5%和68.8%。健康状态和病情加重状态之间以及不同年龄组之间均无显著差异。与以前的可重复性标准相比，该年龄组儿童能够进行的可重复测量显著更多（p < 0.0001）。
与以前的标准相比，2007年美国胸科学会/欧洲呼吸学会的指南简化了4岁及以上至7岁以下儿童用力呼气动作的可重复性评估。在病情加重状态下，可重复性并未降低。该年龄组74.6%的儿童能够得出可重复的肺功能测量结果。
