刺矶松苷I，一种来自刺矶松的新型黄酮醇苷。

Gmelinoside I, a new flavonol glycoside from Limonium gmelinii.

作者信息

Kozhamkulova Zhanar A, Radwan Mohamed M, Zhusupova Galiya E, Abilov Zharilkasin Zh, Rahadilova Saniya N, Ross Samir A

机构信息

Al-farabi Kazakh National University, School of Chemistry, Department of Organic and Natural Products Chemistry, Kazakhstan.

出版信息

Nat Prod Commun. 2010 Jul;5(7):1061-2.

PMID:20734940

Abstract

Gmelinoside I (1), a new flavonol glycoside, was isolated and chemically characterized as 3,5,7,3',4',5'-hexahydroxy-3-O-alpha-D-galactopyranosylflavone from the aerial part of Limonium gmelinii Kuntze (Plumbaginaceae).. Other compounds were identified as (-)-epigallocatechin-3-O-gallate, myricetin, myricetin-3-O-alpha-L-rhamnopyranoside, myricetin-3-O-beta-D-galactoside-6"-O-gallate and caprolactam. The antibacterial, antifungal and antileishmanial activities of the isolated compounds were evaluated. Myricetin showed moderate antileishmanial activity.

摘要

甘紫菜苷I（1）是一种新的黄酮醇苷，从甘紫菜（蓝雪科）的地上部分分离得到，并经化学鉴定为3,5,7,3',4',5'-六羟基-3-O-α-D-吡喃半乳糖基黄酮。其他化合物被鉴定为（-）-表没食子儿茶素-3-O-没食子酸酯、杨梅素、杨梅素-3-O-α-L-鼠李糖苷、杨梅素-3-O-β-D-半乳糖苷-6''-O-没食子酸酯和己内酰胺。对分离得到的化合物的抗菌、抗真菌和抗利什曼原虫活性进行了评估。杨梅素表现出中等的抗利什曼原虫活性。