Azebaze A G B, Ouahouo B M W, Vardamides J C, Valentin A, Kuete V, Acebey L, Beng V P, Nkengfack A E, Meyer M
Faculty of Science, Department of Chemistry, University of Douala, Douala-Cameroon.
Nat Prod Res. 2008 Mar 10;22(4):333-41. doi: 10.1080/14786410701855811.
The phytochemical study of stem bark of Allanblackia gabonensis has resulted in the isolation and characterisation of one new xanthone derivative, named allanxanthone D, together with 10 known compounds, including 6 xanthones derivatives, allanxanthone A, 1,5-dihydroxyxanthone, 1,7-dihydroxyxanthone and 1,3,6,7-tetrahydroxy-2-(3-methylbut-2-enyl)xanthone, forbexanthone, 6-deoxyisojacareubin, one polyisoprenylated benzophenone, guttiferone F, one flavanol, epicathechin, two phytosterols, beta-sitosterol and campesterol. The structures of these compounds were established on the basis of one- and two-dimensional NMR homo- and hetero-nuclear evidence. These compounds were evaluated for their activity against Leishmania amazonensis in vitro and antimicrobial activities against a range of Gram negative and Gram positive bacteria.
对加蓬阿兰布鲁克木茎皮的植物化学研究已分离并鉴定出一种新的氧杂蒽酮衍生物，命名为阿兰氧杂蒽酮D，以及10种已知化合物，包括6种氧杂蒽酮衍生物，阿兰氧杂蒽酮A、1,5 - 二羟基氧杂蒽酮、1,7 - 二羟基氧杂蒽酮和1,3,6,7 - 四羟基 - 2 - (3 - 甲基丁 - 2 - 烯基)氧杂蒽酮、福贝氧杂蒽酮、6 - 脱氧异巴西苏木素，一种多异戊烯基化二苯甲酮，加特菲酮F，一种黄烷醇，表儿茶素，两种植物甾醇，β - 谷甾醇和菜油甾醇。这些化合物的结构是基于一维和二维核磁共振同核和异核证据确定的。对这些化合物进行了体外抗亚马逊利什曼原虫活性以及对一系列革兰氏阴性和革兰氏阳性阳性细菌的抗菌活性评估。
