高血压患者的生活质量、呼吸困难和心室功能。

Quality of life, dyspnea and ventricular function in patients with hypertension.

机构信息

Faculty of Medical Sciences, University of Campinas, SP, Brazil.

出版信息

J Adv Nurs. 2010 Oct;66(10):2287-96. doi: 10.1111/j.1365-2648.2010.05396.x. Epub 2010 Aug 23.

DOI:10.1111/j.1365-2648.2010.05396.x

PMID:20735508

Abstract

AIM

This paper is a report of an investigation of the relationship between health-related quality of life and left ventricular function among patients with hypertension who did not fulfil the criteria for heart failure.

BACKGROUND

Heart failure is a common consequence of hypertension, with Doppler echocardiography being the gold-standard tool to evaluate left ventricular function, mainly hypertension-induced left ventricular damage. Echocardiographic data indicating poorer ventricular function have been related to lower levels of health-related quality of life in patients with systolic and/or diastolic heart failure. However, data are still lacking regarding the correlation between health-related quality of life and left ventricular function and structure in patients with hypertension who do not fulfil the criteria for heart failure.

METHOD

Between September 2005 and February 2007, 98 patients with hypertension without systolic or diastolic heart failure were evaluated. Health-related quality of life was assessed using the Medical Outcomes Study Short Form-36. Left ventricular function was evaluated through Tissue Doppler echocardiography.

RESULTS

Statistically significant but weak correlations (varying from r = -0.22 to 0.35) were observed between some of the Short Form-36 domains and echo data. To consider the potential effect of dyspnoea in this relationship, patients were split according to the presence or absence of the symptom. In the subgroup without dyspnoea, similar patterns of correlation were observed (varying from r = 0.26 to 0.32). In the subgroup with dyspnoea, however, more and stronger correlations were observed between echo data and health-related quality of life domains, varying from r = -0.40 to 0.50.

CONCLUSION

Nurses should be aware of the relevance of evaluating the functional echocardiographic data of patients who not fulfil heart failure criteria, but who experience dyspnoea in order to implement appropriate action plans.

摘要

目的

本研究旨在探讨未达到心力衰竭标准的高血压患者健康相关生活质量与左心室功能之间的关系。

背景

心力衰竭是高血压的常见后果，多普勒超声心动图是评估左心室功能的金标准工具，主要用于评估高血压引起的左心室损伤。超声心动图数据显示心室功能较差与收缩性和/或舒张性心力衰竭患者的健康相关生活质量水平较低相关。然而，对于未达到心力衰竭标准的高血压患者，其健康相关生活质量与左心室功能和结构之间的相关性仍缺乏相关数据。

方法

2005 年 9 月至 2007 年 2 月，共评估了 98 例无收缩性或舒张性心力衰竭的高血压患者。采用医疗结局研究短式 36 健康调查量表评估健康相关生活质量。采用组织多普勒超声心动图评估左心室功能。

结果

部分短式 36 健康调查量表各领域与超声心动图数据之间存在统计学上显著但较弱的相关性（相关系数范围从 r = -0.22 到 0.35）。为了考虑该相关性中呼吸困难的潜在影响，根据是否存在该症状将患者进行了分组。在无呼吸困难的亚组中，观察到相似的相关模式（相关系数范围从 r = 0.26 到 0.32）。然而，在有呼吸困难的亚组中，超声心动图数据与健康相关生活质量各领域之间存在更多且更强的相关性，相关系数范围从 r = -0.40 到 0.50。