Department of Radiology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
J Thorac Imaging. 2011 May;26(2):W51-3. doi: 10.1097/RTI.0b013e3181d29dfd.
A 33-year-old male patient was admitted to our nephrology department with rapidly deteriorating general health, fever, respiratory difficulties, and acute renal failure. Computed tomography of the thorax revealed interstitial edema with thickening of the interlobular septa, peribronchial cuffing, ground-glass opacities, and small pleural and pericardial effusions. Polymerase chain reaction tests verified Puumala virus infection. The patient recovered with supportive treatment. Hantavirus infection should be considered in the differential diagnosis of young patients who present with acute renal failure of an unknown origin and the nonspecific radiologic finding of noncardiogenic interstitial edema, which in combination with typical clinical symptoms and laboratory parameters, can be indicative of this disease.
一位 33 岁男性患者因健康状况迅速恶化、发热、呼吸困难和急性肾衰竭而被收入我们的肾病科。胸部计算机断层扫描显示间质性水肿,小叶间隔增厚,支气管周围袖口征,磨玻璃样混浊,以及少量胸膜和心包积液。聚合酶链反应检测证实为普马拉病毒感染。患者经支持治疗后康复。对于出现不明原因急性肾衰竭和非心源性间质性水肿非特异性放射学表现的年轻患者,应考虑汉坦病毒感染的鉴别诊断,结合典型的临床症状和实验室参数,可提示该疾病。