Kushnerova N F, Fomenko S E, Rakhmanin Iu A, Lesnikova L N, Sprygin V G, Kushnerova T V, Merzliakov V Iu
Gig Sanit. 2010 May-Jun(3):71-4.
The aim of the investigation was to use the biologically active additive (BAD) Kalifen to prevent metabolic disturbances in medical workers during their occupational activity. Female physicians aged 40-50 years were examined. Group 1 (control) included 20 age-matched healthy female donors. Group 2 comprised 27 female physicians (anesthesiologists and surgeons) daily exposed to stresses (chemical, psychoemotional, work-related, etc.) who were asked after blood biochemical tests to daily take the BAD Kalifen in a dose of 2.5 ml after a meal (they made up Group 3), which is equal to the daily prophylactic dose in 100 mg of total polyphenols. The plasma tested before an experiment showed hypertriglyceridemia and hypercholesterolemia, suppressed hepatic etherifying function, imbalance of the fractional content of phospholipids, exhaustion of the antioxidative system, increased lipid peroxidation, and impaired erythrocytic membrane permeability. The prophylactic use of the BAD Kalifen eliminates stress-induced metabolic disturbances and increases occupational and biological longevity in the able-bodied population.
该研究的目的是使用生物活性添加剂（BAD）Kalifen来预防医护人员在职业活动期间的代谢紊乱。对40至50岁的女性医生进行了检查。第1组（对照组）包括20名年龄匹配的健康女性献血者。第2组由27名女性医生（麻醉师和外科医生）组成，她们每天承受压力（化学、心理情绪、工作相关等），在血液生化测试后，她们被要求每天餐后服用2.5毫升的BAD Kalifen（她们组成了第3组），这相当于100毫克总多酚的每日预防剂量。实验前检测的血浆显示出高甘油三酯血症和高胆固醇血症、肝脏醚化功能受抑制、磷脂分数含量失衡、抗氧化系统耗竭、脂质过氧化增加以及红细胞膜通透性受损。预防性使用BAD Kalifen可消除压力引起的代谢紊乱，并提高健康人群的职业寿命和生物寿命。
