Roshchina G Ia, Koroleva V I, Davydov V I
Zh Vyssh Nerv Deiat Im I P Pavlova. 2010 May-Jun;60(3):352-63.
The EEG spectral analysis applied to electrical brain activity of rabbits in the state of animal hypnosis revealed a 2-4-fold increase in the power of the sigma frequency band (12-17 Hz) and a 1.5-2-fold decrease in the gamma frequency (especially 40-70 Hz) in addition to well-known growth of delta (0.3-3 Hz) and reduction of theta activity (4-8 Hz). The changes were more prominent in the frontal cortex areas. The influence of hypnotic state on cortical gamma activity pharmacologically augmented by ketamine injection was analyzed. Administration of subanesthetic ketamine doses led to behavioral locomotor excitation of an animal accompanied by a long-lasting (up to 2 h) increase in the gamma electrical activity. If the animal hypnosis was induced after the ketamine injection, it resulted in an almost instant reorganization of the spectral power. The slow-wave power increased and the gamma-power decreased to the baseline levels. Thus, the animal hypnosis eliminated the reorganization of cortical rhythmicity produced by ketamine, which suggests a stabilizing and, to a certain extent, protective function of this kind of hypnosis in the states of behavioral locomotion and stress.
对处于动物催眠状态的兔子脑电活动进行的脑电图频谱分析显示，除了众所周知的δ波（0.3 - 3Hz）功率增加和θ波活动（4 - 8Hz）减少外，σ频段（12 - 17Hz）的功率增加了2 - 4倍，γ频段（特别是40 - 70Hz）的功率降低了1.5 - 2倍。这些变化在额叶皮质区域更为明显。分析了催眠状态对氯胺酮注射药理学增强的皮质γ活动的影响。给予亚麻醉剂量的氯胺酮会导致动物行为性运动兴奋，并伴有γ电活动的长期（长达2小时）增加。如果在注射氯胺酮后诱导动物催眠，则会导致频谱功率几乎立即重新组织。慢波功率增加，γ功率降至基线水平。因此，动物催眠消除了氯胺酮引起的皮质节律性重新组织，这表明这种催眠在行为运动和应激状态下具有稳定作用，并在一定程度上具有保护功能。
