The economic burden.

Not only is chemo fog a troublesome medical problem for the sufferers, but in addition it is the source of nearly $300 million in direct and indirect expense in the United States alone each year. And since it often persists for extended periods of time, the indirect costs, which stem mainly from lost productivity, continue to accumulate with another nearly $250 million added to the overall cost each year. This is not the highest economic burden for common diseases, but it is a significant amount that could be mostly avoided if biomedical scientists were to find a means to employ safer chemotherapeutic agents.