Institute of Sports Science, Seoul National University, Seoul, Korea.
Int J Sport Nutr Exerc Metab. 2010 Aug;20(4):275-81. doi: 10.1123/ijsnem.20.4.275.
The purpose of this study was to assess differences in the levels of plasma visfatin among female adolescents and changes in plasma visfatin and insulin resistance in obese female adolescents after 12 wk of aerobic exercise training. Twenty normal-weight female students (body-mass index [BMI] < 22.9 kg/m² and body fat ≤ 29.9) and 18 obese female students (BMI ≥ 25 kg/ m² and body fat ≥ 30%) participated in this study. Eleven obese students were assigned to an exercise group and completed a 12-wk aerobic exercise-training program that included four 40- to 50-min sessions per wk with an energy expenditure of 300-400 kcal/d. Seven obese students were assigned to a control group that received no exercise sessions or dietary restriction. The plasma visfatin levels of obese female adolescents were significantly higher (p < .05) than those of the normal-weight female adolescents. The plasma visfatin levels (294.00 ± 124.74 ng/ml to 185.55 ± 67.30 ng/ml, p < .01) and insulin resistance (p < .05) were significantly reduced after 12 wk of aerobic exercise. The results suggest that aerobic exercise resulting in an energy expenditure of 1,200-1,600 kcal/wk for 12 wk decreases plasma visfatin and insulin resistance in obese female adolescents.
本研究旨在评估女性青少年血浆内脂素水平的差异，以及肥胖女性青少年经过 12 周有氧运动训练后血浆内脂素和胰岛素抵抗的变化。本研究纳入了 20 名正常体重的女性学生（体重指数[BMI] < 22.9 kg/m² 且体脂率 ≤ 29.9%）和 18 名肥胖女性学生（BMI ≥ 25 kg/m² 且体脂率 ≥ 30%）。11 名肥胖学生被分配到运动组，并完成了 12 周的有氧运动训练计划，每周进行 4 次 40-50 分钟的运动，能量消耗为 300-400 千卡/天。7 名肥胖学生被分配到对照组，对照组不进行运动或饮食限制。肥胖女性青少年的血浆内脂素水平明显高于（p <.05）正常体重的女性青少年。经过 12 周的有氧运动后，血浆内脂素水平（294.00 ± 124.74 ng/ml 至 185.55 ± 67.30 ng/ml，p <.01）和胰岛素抵抗（p <.05）显著降低。结果表明，每周进行 1200-1600 千卡的有氧运动 12 周可以降低肥胖女性青少年的血浆内脂素水平和胰岛素抵抗。
