Chen C C, Moore E C, McCall B L
Cancer Res. 1978 Jul;38(7):1885-8.
Adult rat liver contained variant forms of thioredoxin reductase with isoelectric points at pH 4.9 and at approximately pH 4.7 compared to pH 5.1 for the enzyme from Novikoff ascites hepatoma. Fetal and regenerating liver contained only the form with the isoelectric point at pH 4.9. All three enzymes precipitated with and were inhibited by a rabbit antibody to purified enzyme from Novikoff tumor.
成年大鼠肝脏中含有硫氧还蛋白还原酶的多种变体形式，其等电点分别为pH 4.9和约pH 4.7，而诺维科夫腹水肝癌中的该酶等电点为pH 5.1。胎儿肝脏和再生肝脏中仅含有等电点为pH 4.9的那种形式。这三种酶都能与针对诺维科夫肿瘤纯化酶的兔抗体发生沉淀反应，并被其抑制。
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