Ismael S
Department of Child Health, Faculty of Medicine, University of Indonesia Jakarta.
Paediatr Indones. 1990 Mar-Apr;30(3-4):79-96.
We report 28 cases diagnosed as GBS in the Department of Child Health, Medical School, University of Indonesia, DR. Cipto Mangunkusumo General Hospital in 7 years period. There were 17 males and 11 females with a ratio of 1.5:1. The age ranged from 9 months to 9.5 years, with a mean age of 4.57 +/- 2.36 years. Twelve (42.86%) cases were preceded by acute respiratory infection, 8 (28.57%) cases by non specific fever, 1 (9.57%) case by gastrointestinal tract infection and 7 (25%) cases did not have any history of acute infection. The clinical manifestations were motor weakness (100%), cranial nerves involvement (14.29%) and disturbance of sensation (17.80%). Most cases (92.86%) showed albuminocytologic dissociation feature with the CSF protein content more than 40 mg/dl. The number of cells was less than 10 cells/mm3 in 96.43% of cases. The specific NCV feature (peripheral NCV decrease) was found in 96.15% of patients and only 1 patient (3.85%) showed normal peripheral NCV. The severity of the disease was in accordance with the prognosis later. Corticosteroid was not beneficial in the treatment of GBS.
我们报告了印度尼西亚大学医学院儿童健康系、Cipto Mangunkusumo 综合医院在 7 年期间诊断为格林-巴利综合征（GBS）的 28 例病例。其中男性 17 例，女性 11 例，男女比例为 1.5:1。年龄范围为 9 个月至 9.5 岁，平均年龄为 4.57±2.36 岁。12 例（42.86%）在发病前有急性呼吸道感染，8 例（28.57%）有非特异性发热，1 例（9.57%）有胃肠道感染，7 例（25%）无急性感染病史。临床表现为运动无力（100%）、颅神经受累（14.29%）和感觉障碍（17.80%）。大多数病例（92.86%）表现出蛋白细胞分离特征，脑脊液蛋白含量超过 40mg/dl。96.43%的病例细胞数少于 10 个/mm³。96.15%的患者发现有特异性神经传导速度（NCV）特征（周围神经传导速度降低），仅 1 例患者（3.85%）周围神经传导速度正常。疾病的严重程度与后期预后一致。皮质类固醇对格林-巴利综合征的治疗无益。
