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[哌仑西平对人体进食期间胆囊容积及进食后胆囊排空的影响]

[Effect of pirenzepine on gallbladder volume during eating and gallbladder emptying after eating in humans].

作者信息

Kucio C, Sliwiński Z, Jonderko K, Nowak A

机构信息

Katedry i Kliniki Gastroenterologii Sl. AM w Katowicach.

出版信息

Pol Arch Med Wewn. 1990 Nov;84(5):292-5.

PMID:2075121
Abstract

The effect of pirenzepine (50 mg p.o.) vs placebo on the fasted gallbladder emptying after a test meal was examined in a double-blind study on 14 healthy male volunteers by means of an ultrasonographic method. Pirenzepine inhibited significantly the meal-induced gallbladder emptying, whereas no significant effect of this drug on the fasted gallbladder volume was observed.

摘要

在一项针对14名健康男性志愿者的双盲研究中,通过超声检查法,研究了哌仑西平(口服50毫克)与安慰剂对试餐后空腹胆囊排空的影响。哌仑西平显著抑制了进餐引起的胆囊排空,而未观察到该药物对空腹胆囊容积有显著影响。

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