肺结核中的高钙血症

Hypercalcemia in pulmonary tuberculosis.

作者信息

Lind L, Ljunghall S

机构信息

Department of Internal Medicine, University Hospital, Uppsala, Sweden.

出版信息

Ups J Med Sci. 1990;95(2):157-60. doi: 10.3109/03009739009178584.

DOI:10.3109/03009739009178584

PMID:2075643

Abstract

Tuberculosis can affect calcium metabolism, mainly through an enhanced production of active vitamin D. The incidence of hypercalcemia among unselected patients with active pulmonary tuberculosis was investigated, retrospectively, during a ten-year period. Among 67 patients, the mean serum calcium concentration on admission was significantly raised compared to healthy controls (2.51 +/- 0.16 (SD) vs 2.43 +/- 0.07 mmol/l; p less than 0.001) and 25% of the patients had hypercalcemia. After one year of successful tuberculostatic treatment the serum calcium values had normalized.

摘要

结核病可影响钙代谢，主要是通过增加活性维生素D的生成。我们对10年间未经挑选的活动性肺结核患者高钙血症的发生率进行了回顾性研究。67例患者中，入院时血清钙平均浓度与健康对照相比显著升高（分别为2.51±0.16（标准差）mmol/L和2.43±0.07 mmol/L；p<0.001），25%的患者有高钙血症。经过一年成功的抗结核治疗后，血清钙值恢复正常。