活动性肺结核中的高钙血症及其与疾病影像学范围的关系。

Hypercalcemia in active pulmonary tuberculosis and its occurrence in relation to the radiographic extent of disease.

作者信息

Chan T Y, Chan C H, Shek C C, Davies P D

机构信息

Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT.

出版信息

Southeast Asian J Trop Med Public Health. 1992 Dec;23(4):702-4.

PMID:1298076

Abstract

The prevalence of hypercalcemia in tuberculosis in Hong Kong and its occurrence in relation to the radiographic extent of disease were studied in 57 patients with sputum smear (n = 44) and/or culture positive (n = 13) pulmonary tuberculosis and in five patients with military tuberculosis prior to treatment. Only one (1.6%) patient had a corrected plasma calcium level above the reference range for our laboratory. There was a positive relationship between the corrected plasma calcium levels and the radiographic extent of disease (r = 0.37), p < 0.01). As the occurrence of hypercalcemia in tuberculosis is known to be influenced by the calcium intake, our finding of a low prevalence of "absolute" hypercalcemia in Hong Kong could be related to the low dietary calcium intake in these subjects.

摘要

我们对57例痰涂片阳性（n = 44）和/或培养阳性（n = 13）的肺结核患者以及5例治疗前的粟粒性肺结核患者进行了研究，以探讨香港地区结核病患者高钙血症的患病率及其与疾病影像学范围的关系。仅有1例（1.6%）患者的校正血浆钙水平高于我们实验室的参考范围。校正血浆钙水平与疾病的影像学范围之间存在正相关关系（r = 0.37，p < 0.01）。由于已知结核病中高钙血症的发生受钙摄入量的影响，我们在香港发现的“绝对”高钙血症低患病率可能与这些受试者的低膳食钙摄入量有关。