5-氟尿嘧啶对体内表皮DNA合成的抑制作用：5-氟尿嘧啶制剂与前体药物效果的比较 - Suppr

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超能文献

The effect of 5-fluorouracil on inhibition of epidermal DNA synthesis in vivo: a comparison of the effect of formulations and a prodrug of 5-FU.

作者信息

Sloan K B, Sherertz E F, McTiernan R G

机构信息

University of Florida, Department of Medicinal Chemistry, Gainesville 32610.

出版信息

Arch Dermatol Res. 1990;282(7):484-6. doi: 10.1007/BF00402629.

DOI:10.1007/BF00402629

PMID:2078053

Abstract

摘要

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Effects of vehicles and prodrug properties and their interactions on the delivery of 6-mercaptopurine through skin: bisacyloxymethyl-6-mercaptopurine prodrugs.载体和前药性质及其相互作用对6-巯基嘌呤经皮递送的影响：双酰氧基甲基-6-巯基嘌呤前药

J Pharm Sci. 1987 Aug;76(8):587-95. doi: 10.1002/jps.2600760803.

Topical drug effects on normal and proliferating epidermal cell models.

Arch Dermatol. 1981 Jul;117(7):394-8.

Epidermal DNA synthesis: a new disc technique for evaluating incorporation of tritiated thymidine.表皮DNA合成：一种用于评估氚标记胸腺嘧啶核苷掺入情况的新圆盘技术。

J Invest Dermatol. 1980 Nov;75(5):375-8. doi: 10.1111/1523-1747.ep12523612.

Further studies with topical 5-fluorouracil.外用5-氟尿嘧啶的进一步研究。

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An animal model for screening topical and systemic drugs for potential use in the treatment of psoriasis.一种用于筛选局部和全身用药以评估其治疗银屑病潜在用途的动物模型。

J Invest Dermatol. 1975 Aug;65(2):235-7. doi: 10.1111/1523-1747.ep12598248.

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