复方新诺明与氯霉素治疗伤寒的对比试验。
Comparative trial of Co-trimoxazole and Chloramphenicol in Typhoid Fever.
作者信息
Sardesai H V, Karandikar R S, Harshe R G
出版信息
Br Med J. 1973 Jan 13;1(5845):82-3. doi: 10.1136/bmj.1.5845.82.
Abstract
A comparative trial of co-trimoxazole and chloramphenicol was conducted in two groups of 50 patients each to try to resolve conflicting opinions on the relative merits of the two drugs in the treatment of typhoid fever. We conclude that in our part of India co-trimoxazole is superior to chloramphenicol and that differences in our findings to those of others may perhaps be accounted for by differences in strains of Salmonella typhi, ethnic differences, and possibly differences in herd immunity to typhoid.
摘要
对复方新诺明和氯霉素进行了一项对比试验，两组各有50名患者，旨在解决关于这两种药物治疗伤寒热相对优缺点的相互矛盾的观点。我们得出结论，在印度我们所在的地区，复方新诺明优于氯霉素，我们的研究结果与其他人的结果存在差异，这可能是由伤寒杆菌菌株差异、种族差异以及可能的人群对伤寒的免疫力差异造成的。
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